Spectinomycin dihydrochloride pentahydrate
Spectinomycin dihydrochloride pentahydrate (CAS: 22189-32-8) is an aminocyclitol antibiotic derived from <i>Streptomyces spectabilis</i>. With the molecular formula C14H24N2O7 · 2HCl · 5H2O and a molecular weight of 495.35, this compound is primarily used in biotechnology and cell biology applications. It serves as a selection marker in plant transformation systems and is valuable for studying respiratory tract infections in cattle and generating plants deficient in plastid-encoded RNA polymerase.
Antibacterial Agent
Spectinomycin is an aminocyclitol antibiotic effective against a range of bacteria. It has been used clinically for treating certain bacterial infections, such as acute gonorrheal urethritis and cervicitis.
Plant Transformation Selection Marker
In plant biotechnology, it functions as a selection marker (Spcr) for plant cells containing the marker gene. This aids in identifying successfully transformed plant cells for further development.
Cell Biology Research
Used to mark cell layers for monitoring cell fate during leaf development and to generate plants deficient for plastid-encoded RNA polymerase on MS-agar media, aiding in fundamental cell biology studies.
Research in Veterinary Medicine
Investigated for its efficacy in treating respiratory tract infections in cattle caused by specific bacterial pathogens like <i>Pasteurella multocida</i> and <i>Mannheimia haemolytica</i>.
Plasmid Amplification
Spectinomycin is also employed in molecular biology for the amplification of low-copy-number plasmids that carry specific replicons, supporting genetic research.
| Molecular weight | 495.35 |
|---|---|
| Empirical formula | C14H24N2O7 · 2HCl · 5H2O |
| Assay | ≥98.0% |
| Grade | Biotechnology Performance Certified |
| Storage temperature | 2-8°C |
| Impurities tested | endotoxin, tested |
| Application | Spectinomycin is an aminocyclitol antibiotic derived from Streptomyces spectabilis. It has been shown to have a wide variety of uses, including treating acute gonorrheal urethritis and cervictis†, to mark cell layers to monitor cell fate during leaf development†, as a selection marker in plant related transformation systems for plant cells containing the marker gene Spcr, to study respiratory tract infections of cattle caused by Pasteurella multocida and Mannheimia haemolytica†, and to generate plants deficient for the plastid-encoded RNA polymerase on MS-agar media†. Spectinomycin also has use in amplification of low copy number plasmid carrying replicons. It is recommended for use in cell culture applications at 7.5-20 mg/L. |
| Suitability | cell culture tested |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 2 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Potency | ≥603 μg per mg |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Spectinomycin dihydrochloride pentahydrate used for?
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Spectinomycin dihydrochloride pentahydrate is used as an antibacterial agent, a selection marker in plant transformation systems, in cell biology research for studying cell fate and generating specific plant mutants, and in veterinary research for treating cattle respiratory infections. It is also used for plasmid amplification.
What is the CAS number and chemical formula?
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The CAS number is 22189-32-8 and the chemical formula is C14H24N2O7 · 2HCl · 5H2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Spectinomycin dihydrochloride pentahydrate in 'Biotechnology Performance Certified' grade with an assay of ≥98.0% and a potency of ≥603 μg per mg. It is tested for endotoxins and suitability for cell culture. TSS does not represent this product as USP, BP, or EP grade.
What are the safety and handling precautions for this chemical?
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This chemical requires careful handling. Personal protective equipment, including eyeshields and gloves, is essential. A respirator filter, such as type N95 (US) or type P1 (EN143), should be used. Refer to the safety data sheet for comprehensive handling information.
How is this product shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. We adhere to all regulations for the safe packaging, shipping, and export of chemical products worldwide.
How can I request a sample or a quote?
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To request a sample or a quote for Spectinomycin dihydrochloride pentahydrate, please contact our sales team through the website or by phone.
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