Spermidine

CAS 124-20-9NH2(CH2)3NH(CH2)4NH2Biochemicals & Reagents

Spermidine (CAS: 124-20-9), with the linear formula NH 2 (CH 2 ) 3 NH(CH 2 ) 4 NH 2 and a molecular weight of 145.25 g/mol, is a polyamine with significant biological roles. It is crucial for cell growth, differentiation, and survival. Spermidine is widely utilised in biochemical research, particularly in studies concerning cell signalling, longevity, and nitric oxide metabolism.

IUPAC: 1,8-Diamino-4-azaoctane,N-(3-Aminopropyl)-1,4-diaminobutane

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Spermidine (NH2(CH2)3NH(CH2)4NH2) — chemical structure, CAS 124-20-9; Life Science, fine chemical supplied by Tech Serve Solutions

Application IndexBioactive Small MoleculesBiochemicals and ReagentsCell BiologyCell Signaling EnzymesEnzymesInhibitorsand SubstratesNOS InhibitorsNitric Oxide Metabolism

01 /Applications

Biochemical Research

Spermidine is an essential reagent in biochemical laboratories for investigating cellular processes, including autophagy and epigenetics. Its role in cell signalling pathways makes it valuable for studying age-related diseases and cellular stress responses.

Cell Culture Applications

Due to its suitability for cell culture, spermidine is used to support cell growth and viability in various experimental settings. It can influence cell proliferation and differentiation, making it a key component in specific cell culture media formulations.

Nitric Oxide Metabolism Studies

As a regulator of nitric oxide synthase (NOS) and involved in nitric oxide metabolism, spermidine is a critical compound for researchers studying cardiovascular health and inflammatory processes. It acts as a substrate and modulator in these pathways.

02 /Properties

Molecular weight	145.25
Linear formula	NH2(CH2)3NH(CH2)4NH2
Assay	≥99.0% (GC)
Density	0.925 g/mL at 25 °C(lit.)
Refractive index	n20/D 1.479(lit.)
Storage temperature	room temp
Suitability	suitable for cell culture

03 /Safety & handling

GHS hazard pictogram: Corrosive (GHS05) — Corrosive

Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P280Wear protective gloves, clothing and eye/face protection
P305IF IN EYES
P310Immediately call a POISON CENTER or doctor

Protective equipment	Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Flash point	112 °C / 233.6 °F
Transport (UN / ADR)	UN 2735PSN2 8 / PGII
Water hazard class (WGK, DE)	3
Hazard codes (EU)	C
Risk statements (R)	34
Safety statements (S)	26-36/37/39-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

124-20-9

MDL number

MFCD00008229

PubChem substance

24899590

Beilstein registry

1698591

05 /Additional specifications

Product Line	BioReagent
Gene Information	rat ... Ppm1a(24666)

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is Spermidine used for?

Spermidine is primarily used in biochemical research, cell culture applications, and studies concerning nitric oxide metabolism and cell signalling.

What is the CAS number and formula for Spermidine?

Spermidine has the CAS number 124-20-9 and its linear formula is NH 2 (CH 2 ) 3 NH(CH 2 ) 4 NH 2 .

What grade and purity does Tech Serve Solutions supply for Spermidine?

Tech Serve Solutions supplies Spermidine with an assay of ≥99.0% (GC). We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.

What are the safety and handling precautions for Spermidine?

Spermidine is classified as a danger substance, indicated by the GHS05 symbol and signal word 'Danger'. It causes severe skin burns and eye damage (H314). Appropriate personal protective equipment, including face shields, full-face respirators, gloves, and goggles, is mandatory during handling. Refer to the safety data sheet for detailed guidance.

How is Spermidine packed, shipped, and exported?

Spermidine is packed, shipped, and exported in compliance with relevant transportation regulations, including UN 2735 for hazardous materials, with appropriate hazard classification and packaging group.

How can I request a quote or sample of Spermidine?

To request a quote or a sample of Spermidine, please contact our sales team through the TSS website or via direct inquiry, providing your specific requirements.