13-cis-Retinal
13-cis-Retinal (CAS: 472-86-6), a derivative of vitamin A with the molecular formula C20H28O and a molecular weight of 284.44 g/mol, is a key intermediate in visual phototransduction. It functions as the chromophore in rhodopsin and cone opsins, undergoing photoisomerization upon light absorption. This process initiates the visual cascade. It is also utilized in various biochemical research applications and as a building block in organic synthesis.
- IUPAC
- 13-cis-Vitamin A aldehyde,Vitamin A aldehyde

Biochemical Research
Serves as a critical component in studies of vision and photoreceptor mechanisms. Its role in the visual cycle makes it invaluable for understanding light detection at a molecular level.
Organic Synthesis
Used as a chemical intermediate and building block for the synthesis of complex organic molecules, particularly those related to retinoids and isoprenoids.
Retinoid Studies
Investigates the biological activity and chemical properties of retinoids, which are important in cellular differentiation and development.
| Molecular weight | 284.44 |
|---|---|
| Empirical formula | C20H28O |
| Assay | ≥85% (HPLC) |
| Storage temperature | −20°C |

Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H332Harmful if inhaled
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-38 |
| Safety statements (S) | 22-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Shipped In | dry ice |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 13-cis-Retinal used for?
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13-cis-Retinal is primarily used in biochemical research related to vision, serving as the chromophore in rhodopsin and cone opsins. It is also employed as a building block in organic synthesis and for studying retinoid chemistry.
What are the CAS number and formula for 13-cis-Retinal?
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The CAS number for 13-cis-Retinal is 472-86-6, and its molecular formula is C20H28O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 13-cis-Retinal with an assay of ≥85% (HPLC). We do not represent this product as USP, BP, EP, or other pharmacopoeia grades.
How is 13-cis-Retinal stored and shipped?
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13-cis-Retinal requires storage at -20°C and is shipped using dry ice to maintain its stability and integrity.
What are the main hazards associated with 13-cis-Retinal?
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13-cis-Retinal is classified with the GHS signal word 'Warning' and hazard statements H302 (Harmful if swallowed), H312 (Harmful in contact with skin), H315 (Causes skin irritation), and H332 (Harmful if inhaled). Appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves, should be used.
How can I request a quote or sample for 13-cis-Retinal?
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To request a quote or sample for 13-cis-Retinal, please contact our sales team through the TSS website or via direct inquiry.
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