15-Crown-5
1,4,7,10,13-Pentaoxacyclopentadecane, commonly known as 15-Crown-5 (CAS: 33100-27-5), is a cyclic polyether with the chemical formula C10H20O5 and a molecular weight of 220.26 g/mol. This compound is a versatile reagent primarily utilised in chemical synthesis and for chelation and complexation applications, particularly with alkali metal cations.
- IUPAC
- 1,4,7,10,13-Pentaoxacyclopentadecane
- Synonyms
- 1,4,7,10,13-Pentaoxacyclopentadecane

Chelation and Complexation
15-Crown-5 is highly effective at selectively binding to metal cations, especially sodium (Na+), due to its cavity size. This property makes it useful in various separation and extraction processes.
Chemical Synthesis
As a crown ether, 15-Crown-5 can activate anions by complexing the accompanying cation, thereby increasing the reactivity of nucleophiles in organic reactions. It is employed in facilitating reactions in non-polar solvents.
Phase Transfer Catalysis
It can function as a phase transfer catalyst, enabling reactions between reactants in immiscible phases, such as aqueous and organic layers, by transporting cations into the organic phase.
| Molecular weight | 220.26 |
|---|---|
| Empirical formula | C10H20O5 |
| Assay | 98% |
| Grade | Vetec™ reagent grade |
| Boiling point | 93-96 °C/0.05 mmHg(lit.) |
| Density | 1.113 g/mL at 20 °C(lit.) |
| Refractive index | n20/D 1.465(lit.) |

Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
Precautionary statements
- P305IF IN EYES
| Flash point | 113 °C / 235.4 °F |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 15-Crown-5 used for?
+
15-Crown-5 is primarily used for its ability to chelate and complex metal cations, particularly sodium ions, and in various chemical synthesis applications, often as a phase transfer catalyst.
What are the CAS number and formula for 15-Crown-5?
+
The CAS number for 15-Crown-5 is 33100-27-5, and its empirical formula is C10H20O5.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 15-Crown-5 in Vetec™ reagent grade with an assay of 98%.
How should 15-Crown-5 be handled safely?
+
15-Crown-5 is harmful if swallowed and causes skin and serious eye irritation. Handle with appropriate personal protective equipment, including gloves and eye protection, and ensure good ventilation. Refer to the Safety Data Sheet for detailed handling instructions.
How is 15-Crown-5 packed and exported?
+
15-Crown-5 is carefully packed to maintain its integrity during transit. As a global supplier, Tech Serve Solutions exports this chemical to researchers and industries worldwide, adhering to all relevant shipping regulations.
How can I request a sample or quote for 15-Crown-5?
+
To request a sample or a quote for 15-Crown-5, please contact our sales department through the website or by phone, providing your specific requirements.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis