12-Mercaptododecanoic acid
12-Mercaptododecanoic acid (CAS: 82001-53-4), a functional thiol with the formula C12H24O2S and a molecular weight of 232.38 g/mol, is a key organic building block. It is primarily employed in materials science for the creation of self-assembled monolayers (SAMs). Its carboxylic acid termination allows for further functionalisation, making it suitable for applications in micro/nanoelectronics and advanced chemical synthesis.
- IUPAC
- MDA

Hydrophilic Self-Assembled Monolayers (SAMs)
This compound serves as a precursor for generating hydrophilic SAMs. The carboxylic acid end groups facilitate further modification to introduce diverse functionalities, which is crucial for surface engineering in various advanced applications.
Molecular Ruler Studies
Utilised in research investigating the influence of molecular structure on the precision of copper-bound "molecular ruler" stacks, specifically with mercaptoalkanoic acids. This application highlights its utility in nanoscale metrology and materials characterisation.
Surface Functionalisation
The carboxylic acid functionality enables covalent attachment to various substrates or further reaction with other molecules. This makes it valuable for tailoring surface properties in microelectronics and advanced materials development.
| Molecular weight | 232.38 |
|---|---|
| Empirical formula | C12H24O2S |
| Assay | 96% |
| Storage temperature | 2-8°C |
| Application | This compound is used to produce hydrophilic SAMs. The resulting monolayers which are terminated with carboxylic acids can be further functionalized1 to introduce more complex end groups. Used in a study of the effect of molecular structure on the precision of copper-bound α,ω-mercaptoalkanoic acid \"molecular ruler\" stacks.2 |
| Melting point | 45-50 °C |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | >110 °C / >230 °F |
| Transport (UN / ADR) | UN 3335 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 12-Mercaptododecanoic acid used for?
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12-Mercaptododecanoic acid is used in the production of hydrophilic self-assembled monolayers (SAMs) and in studies concerning molecular ruler stacks. Its carboxylic acid end groups allow for further functionalisation.
What are the CAS number and formula for 12-Mercaptododecanoic acid?
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The CAS number for 12-Mercaptododecanoic acid is 82001-53-4 and its formula is C12H24O2S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 12-Mercaptododecanoic acid with an assay of 96%. This product is not represented as USP, BP, or EP grade.
How should 12-Mercaptododecanoic acid be handled safely?
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12-Mercaptododecanoic acid is classified as a Warning substance (GHS07) with hazard statements H315, H319, and H335, indicating it causes skin irritation, serious eye irritation, and may cause respiratory irritation. Recommended personal protective equipment includes a dust mask (N95), eyeshields, and gloves. Handle in a well-ventilated area.
How is 12-Mercaptododecanoic acid packed and shipped?
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12-Mercaptododecanoic acid is stored at 2-8°C. It is shipped as a regulated item (UN 3335).
How can I request a quote or sample?
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To request a quote or sample, please contact our sales department via the website or by phone.
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