Memantine hydrochloride

CAS 41100-52-1C12H21N · HClCell Biology

Memantine hydrochloride (CAS: 41100-52-1; Formula: C12H21N · HCl; MW: 215.76) is an NMDA receptor antagonist. It functions as a voltage-dependent, low-affinity, uncompetitive antagonist at N-methyl-D-aspartate (NMDA) receptors. This compound is primarily recognised for its therapeutic applications, particularly in the management of moderate to severe Alzheimer's disease, by modulating glutamate neurotransmission. It is a key component in neuroscience research.

IUPAC: 3,5-Dimethyl-1-adamantanamine hydrochloride,3,5-Dimethylamantadine hydrochloride
Synonyms: 3,5-Dimethyl-1-adamantanamine hydrochloride3,5-Dimethylamantadine hydrochloride

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Memantine hydrochloride (C12H21N · HCl) — chemical structure, CAS 41100-52-1; Life Science, fine chemical supplied by Tech Serve Solutions

Bioactive Small MoleculesCell BiologyExcitatory Amino AcidsForest LabsIon ChannelsLigand-Gated Ion ChannelsNMDA AntagonistsNeuroscienceNeurotransmissionNeurotransmitters

01 /Applications

Alzheimer's Disease Treatment

Memantine hydrochloride is an approved therapeutic agent used to treat patients with moderate to severe Alzheimer's disease. It helps to improve cognitive function and daily living activities by regulating glutamate activity in the brain.

Neuroscience Research

As a specific NMDA receptor antagonist, it is utilised in laboratory settings to investigate the roles of NMDA receptors in various neurological processes and disease models. This aids in understanding excitotoxicity and neuronal signalling.

Ligand-Gated Ion Channel Studies

The compound serves as a valuable tool for studying the function and modulation of ligand-gated ion channels, specifically NMDA receptors, contributing to a deeper understanding of ionotropic glutamate receptor modulators.

02 /Properties

Molecular weight	215.76
Empirical formula	C12H21N · HCl
Assay	≥98% (GC)

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

41100-52-1

MDL number

MFCD00214336

PubChem substance

24277990

05 /Additional specifications

Gene Information	human ... DRD1(1812), DRD2(1813), DRD3(1814), DRD4(1815), DRD5(1816)

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is Memantine hydrochloride used for?

Memantine hydrochloride is primarily used for the treatment of moderate to severe Alzheimer's disease and in neuroscience research for studying NMDA receptor function.

What are the CAS number and formula for Memantine hydrochloride?

The CAS number for Memantine hydrochloride is 41100-52-1, and its formula is C12H21N · HCl.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Memantine hydrochloride with a purity of ≥98% (GC). We do not represent this product as USP, BP, or EP grade.

What are the safety considerations for Memantine hydrochloride?

When handling Memantine hydrochloride, it is essential to use safety equipment including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. The compound is classified under WGK Germany 3.

How is Memantine hydrochloride packed and shipped?

Memantine hydrochloride is carefully packed to ensure safe transit and is exported globally by Tech Serve Solutions, adhering to all relevant shipping regulations.