(S)-(+)-2-Methylbutyronitrile
(S)-(+)-2-Methylbutyronitrile (CAS: 25570-03-0, Formula: C2H5CH(CH3)CN, MW: 83.13) is a chiral building block utilized in chemical synthesis. This optically active nitrile serves as a valuable intermediate in asymmetric synthesis, enabling the construction of complex molecules with defined stereochemistry. Its properties make it suitable for research and development in organic chemistry, particularly in the synthesis of pharmaceuticals and fine chemicals where chirality is crucial.
Chiral Building Block in Organic Synthesis
(S)-(+)-2-Methylbutyronitrile acts as a key chiral synthon. It allows for the introduction of a specific stereocenter into target molecules, which is vital for the efficacy of many pharmaceutical compounds and biologically active molecules.
Intermediate for Fine Chemicals
This nitrile is employed in the synthesis of various fine chemicals. Its functional groups can be transformed through established chemical reactions to create more complex structures, contributing to the development of novel materials and specialised chemical products.
Asymmetric Synthesis Applications
The enantiomerically pure nature of (S)-(+)-2-Methylbutyronitrile makes it highly useful in asymmetric synthesis. It facilitates reactions that produce a predominance of one enantiomer over the other, a critical requirement in modern drug discovery and development.
| Molecular weight | 83.13 |
|---|---|
| Linear formula | C2H5CH(CH3)CN |
| Assay | 98% |
| Boiling point | 125-126 °C(lit.) |
| Density | 0.786 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.39(lit.) |
| Optical activity | [α]20/D +31°, neat |
| Storage temperature | 2-8°C |
| Application | Chiral building block |
Hazard statements
- H226Flammable liquid and vapour
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H332Harmful if inhaled
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 24 °C / 75.2 °F |
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 10-20/21/22 |
| Safety statements (S) | 16-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(+)-2-Methylbutyronitrile used for?
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(S)-(+)-2-Methylbutyronitrile is primarily used as a chiral building block in organic synthesis and asymmetric synthesis for the development of fine chemicals and pharmaceutical intermediates.
What are the CAS number and formula for (S)-(+)-2-Methylbutyronitrile?
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The CAS number for (S)-(+)-2-Methylbutyronitrile is 25570-03-0, and its linear formula is C2H5CH(CH3)CN.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-(+)-2-Methylbutyronitrile with an assay of 98%. We do not represent this product as USP, BP, or EP grade.
How should (S)-(+)-2-Methylbutyronitrile be handled safely?
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Warning: This product is flammable and harmful if swallowed, in contact with skin, or if inhaled. Handle with appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, in a well-ventilated area. Store at 2-8°C. Refer to the safety data sheet for full details.
Is (S)-(+)-2-Methylbutyronitrile a controlled substance?
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Based on the provided data, (S)-(+)-2-Methylbutyronitrile is not indicated as a controlled substance.
How is (S)-(+)-2-Methylbutyronitrile packed and shipped?
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(S)-(+)-2-Methylbutyronitrile is shipped as a flammable liquid, UN 1993, Hazard Class 3, Packing Group III. Specific packaging details are available upon request, and TSS exports globally.
How can I request a sample or quote for (S)-(+)-2-Methylbutyronitrile?
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To request a sample or quote for (S)-(+)-2-Methylbutyronitrile, please contact our sales team through the website or by phone, providing your specific requirements.
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