(S)-(+)-2-Methylbutyric anhydride
(S)-(+)-2-Methylbutyric anhydride (CAS: 84131-91-9) is a chiral carboxylic acid anhydride with the chemical formula [C2H5CH(CH3)CO]2O and a molecular weight of 186.25 g/mol. This optically active compound, exhibiting a specific rotation of +35° (neat), serves as a valuable chiral building block in organic synthesis. Its defined stereochemistry makes it useful for introducing chiral centres in asymmetric reactions, contributing to the synthesis of complex molecules.
![(S)-(+)-2-Methylbutyric anhydride ([C2H5CH(CH3)CO]2O) — chemical structure, CAS 84131-91-9; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F84131-91-9.png&w=3840&q=75)
Chiral Synthesis
As a chiral auxiliary and building block, (S)-(+)-2-Methylbutyric anhydride is employed in asymmetric synthesis for the stereoselective preparation of complex organic molecules, including pharmaceuticals and agrochemicals.
Organic Synthesis
This compound functions as a reagent in various organic transformations, facilitating acylation reactions and the introduction of chiral moieties into target structures.
Research and Development
Utilised in academic and industrial research laboratories, it aids in exploring novel synthetic pathways and developing new chiral compounds.
| Molecular weight | 186.25 |
|---|---|
| Linear formula | [C2H5CH(CH3)CO]2O |
| Assay | 95% |
| Boiling point | 60 °C/0.2 mmHg(lit.) |
| Density | 0.934 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.418(lit.) |
| Optical activity | [α]20/D +35°, neat |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 90 °C / 194 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-27-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(+)-2-Methylbutyric anhydride used for?
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(S)-(+)-2-Methylbutyric anhydride is primarily used as a chiral building block in asymmetric synthesis for the stereoselective preparation of complex organic molecules. It also finds application as a reagent in acylation reactions within research and development settings.
What is the CAS number and chemical formula for (S)-(+)-2-Methylbutyric anhydride?
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The CAS number for (S)-(+)-2-Methylbutyric anhydride is 84131-91-9, and its chemical formula is [C2H5CH(CH3)CO]2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-(+)-2-Methylbutyric anhydride with an assay of 95%. This product is supplied for research and development purposes and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should (S)-(+)-2-Methylbutyric anhydride be handled safely?
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(S)-(+)-2-Methylbutyric anhydride is classified as Danger (GHS05) and causes severe skin burns and eye damage (H314). Handling requires full personal protective equipment, including full-face respirators, gloves, goggles, and face shields. Ensure adequate ventilation and follow strict safety protocols to avoid contact.
Is (S)-(+)-2-Methylbutyric anhydride a controlled substance?
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The provided data does not indicate that (S)-(+)-2-Methylbutyric anhydride is a controlled substance.
How is (S)-(+)-2-Methylbutyric anhydride packed and exported?
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(S)-(+)-2-Methylbutyric anhydride is packed and exported in accordance with international regulations for hazardous materials. It is classified under UN 3265, 8 / PGII, indicating it is a corrosive liquid, acidic, organic, n.o.s.
How can I request a quote or sample of (S)-(+)-2-Methylbutyric anhydride?
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To request a quote or sample of (S)-(+)-2-Methylbutyric anhydride, please contact our sales team via the website or by calling our dedicated order line.
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