(S)-(+)-2-Methoxy-2-phenylethanol
(S)-(+)-2-Methoxy-2-phenylethanol (CAS: 66051-01-2) is a chiral alcohol with the molecular formula C6H5CH(OCH3)CH2OH and a molecular weight of 152.19 g/mol. As a valuable chiral building block, it finds application in asymmetric synthesis and organic chemical synthesis. Supplied by Tech Serve Solutions, this compound is typically offered at a high purity, suitable for research and development purposes in the chemical and pharmaceutical industries.
- IUPAC
- β-Methoxyphenethyl alcohol,(+)-β-Methoxyphenethyl alcohol

Asymmetric Synthesis
This chiral alcohol serves as a key intermediate in asymmetric synthesis, enabling the stereoselective construction of complex molecules. Its defined stereochemistry makes it useful for introducing chirality into target compounds.
Chiral Building Block
As a versatile chiral building block, (S)-(+)-2-Methoxy-2-phenylethanol is employed in the synthesis of various enantiomerically pure compounds. It is particularly useful in pharmaceutical research and development for creating stereochemically defined active pharmaceutical ingredients (APIs).
Organic Synthesis
Utilised in general organic synthesis, this compound can participate in a variety of reactions, including esterification, oxidation, and etherification. Its unique structure allows for the formation of novel organic molecules with specific functionalities.
| Molecular weight | 152.19 |
|---|---|
| Linear formula | C6H5CH(OCH3)CH2OH |
| Assay | 98% |
| Boiling point | 65 °C/0.1 mmHg(lit.) |
| Density | 1.054 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.52(lit.) |
| Optical activity | [α]19/D +133°, c = 1 in acetone |
| Optical purity | ee: 99% (GLC) |

Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 98 °C / 208.4 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(+)-2-Methoxy-2-phenylethanol used for?
+
(S)-(+)-2-Methoxy-2-phenylethanol is primarily used as a chiral building block in asymmetric synthesis and general organic synthesis. It is valuable for creating stereochemically pure compounds, particularly in pharmaceutical research.
What are the CAS number and formula for (S)-(+)-2-Methoxy-2-phenylethanol?
+
The CAS number is 66051-01-2, and the molecular formula is C6H5CH(OCH3)CH2OH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions typically supplies (S)-(+)-2-Methoxy-2-phenylethanol with an assay of 98% and an optical purity of ee: 99% (GLC). This is a technical/research grade product, and TSS does not represent it as USP/BP/EP.
What are the safety considerations for handling (S)-(+)-2-Methoxy-2-phenylethanol?
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This compound is classified with a Warning signal word and carries hazard statements H302 (Harmful if swallowed), H312 (Harmful in contact with skin), H315 (Causes skin irritation), H319 (Causes serious eye irritation), H332 (Harmful if inhaled), and H335 (May cause respiratory irritation). Appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection, should be used. Refer to the Safety Data Sheet (SDS) for full details.
How is (S)-(+)-2-Methoxy-2-phenylethanol packaged and shipped?
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Tech Serve Solutions handles the packaging and shipping of chemicals with care, adhering to international regulations for the export of laboratory reagents and fine chemicals.
How can I request a sample or quote for (S)-(+)-2-Methoxy-2-phenylethanol?
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To request a sample or a quote, please contact our sales department via the details provided on the Tech Serve Solutions website.
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