(S)-(+)-2-Methylpiperazine
(S)-(+)-2-Methylpiperazine (CAS 74879-18-8, C5H12N2) is a chiral heterocyclic compound with a molecular weight of 100.16 g/mol. It is a valuable building block in organic synthesis, particularly noted for its utility in the preparation of quinoline antibacterials. Supplied by Tech Serve Solutions with an assay of 99%, this compound is suitable for research and chemical synthesis applications where high enantiomeric purity is required.

Synthesis of Quinolone Antibacterials
This chiral piperazine derivative serves as a crucial synthon in the multi-step synthesis of various quinolone-based antibacterial agents, contributing to the development of important pharmaceuticals.
Asymmetric Synthesis
As a chiral building block, (S)-(+)-2-Methylpiperazine is employed in asymmetric synthesis to introduce specific stereochemistry into target molecules, enabling the creation of enantiomerically pure compounds.
Chiral Ligand Development
Its structure makes it a candidate for incorporation into chiral ligands used in asymmetric catalysis, facilitating enantioselective transformations in organic chemistry.
Heterocyclic Chemistry
This compound is a useful intermediate in the broader field of heterocyclic chemistry, allowing for the construction of complex nitrogen-containing ring systems.
| Molecular weight | 100.16 |
|---|---|
| Empirical formula | C5H12N2 |
| Assay | 99% |
| Optical activity | [α]20/D +6.8°, c = 1 in ethanol |
| Application | Valuable synthon for quinoline antibacterials.1 |
| Melting point | 91-93 °C(lit.) |


Hazard statements
- H228Flammable solid
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Flash point | 65 °C / 149 °F |
| Transport (UN / ADR) | UN 1325 4.1 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xi |
| Risk statements (R) | 11-36/37/38 |
| Safety statements (S) | 16-26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(+)-2-Methylpiperazine used for?
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(S)-(+)-2-Methylpiperazine is a valuable synthon for the synthesis of quinoline antibacterials and is utilized in asymmetric synthesis and heterocyclic building block applications.
What is the CAS number and chemical formula for (S)-(+)-2-Methylpiperazine?
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The CAS number for (S)-(+)-2-Methylpiperazine is 74879-18-8, and its chemical formula is C5H12N2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-(+)-2-Methylpiperazine with an assay of 99%. This product is supplied for research and chemical synthesis purposes and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should (S)-(+)-2-Methylpiperazine be handled safely?
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(S)-(+)-2-Methylpiperazine is a flammable solid (H228) and an irritant (H315, H319, H335). Handle with appropriate personal protective equipment, including eye shields, gloves, and respiratory protection (e.g., N95 dust mask or P3 filter), in a well-ventilated area, keeping away from ignition sources.
How is (S)-(+)-2-Methylpiperazine packed and shipped?
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Products are carefully packed according to international shipping regulations. Tech Serve Solutions is a global supplier and exporter, experienced in handling and shipping fine chemicals worldwide.
How can I request a sample or quote for (S)-(+)-2-Methylpiperazine?
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To request a sample or a quotation, please contact our sales team through the website or by phone, providing your details and the required quantity.
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