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(S)-(+)-2-Methylpiperazine

CAS 74879-18-8C5H12N2Chemical Synthesis

(S)-(+)-2-Methylpiperazine (CAS 74879-18-8, C5H12N2) is a chiral heterocyclic compound with a molecular weight of 100.16 g/mol. It is a valuable building block in organic synthesis, particularly noted for its utility in the preparation of quinoline antibacterials. Supplied by Tech Serve Solutions with an assay of 99%, this compound is suitable for research and chemical synthesis applications where high enantiomeric purity is required.

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(S)-(+)-2-Methylpiperazine (C5H12N2) — chemical structure, CAS 74879-18-8; Chemistry, fine chemical supplied by Tech Serve Solutions
Asymmetric SynthesisChemical SynthesisChiral Building BlocksHeterocyclic Building BlocksPiperazines
01 /Applications

Synthesis of Quinolone Antibacterials

This chiral piperazine derivative serves as a crucial synthon in the multi-step synthesis of various quinolone-based antibacterial agents, contributing to the development of important pharmaceuticals.

Asymmetric Synthesis

As a chiral building block, (S)-(+)-2-Methylpiperazine is employed in asymmetric synthesis to introduce specific stereochemistry into target molecules, enabling the creation of enantiomerically pure compounds.

Chiral Ligand Development

Its structure makes it a candidate for incorporation into chiral ligands used in asymmetric catalysis, facilitating enantioselective transformations in organic chemistry.

Heterocyclic Chemistry

This compound is a useful intermediate in the broader field of heterocyclic chemistry, allowing for the construction of complex nitrogen-containing ring systems.

02 /Properties
Molecular weight100.16
Empirical formulaC5H12N2
Assay99%
Optical activity[α]20/D +6.8°, c = 1 in ethanol
ApplicationValuable synthon for quinoline antibacterials.1
Melting point91-93 °C(lit.)
03 /Safety & handling
GHS hazard pictogram: Flammable (GHS02)
Flammable
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Danger

Hazard statements

  • H228Flammable solid
  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H335May cause respiratory irritation

Precautionary statements

  • P210Keep away from heat, sparks and open flames. No smoking
  • P261Avoid breathing dust, fume, gas or vapours
  • P305IF IN EYES
Protective equipmentdust mask type N95 (US), Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Flash point65 °C / 149 °F
Transport (UN / ADR)UN 1325 4.1 / PGII
Water hazard class (WGK, DE)3
Hazard codes (EU)F,Xi
Risk statements (R)11-36/37/38
Safety statements (S)16-26

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
74879-18-8
MDL number
MFCD00171452
PubChem substance
24864688
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (S)-(+)-2-Methylpiperazine used for?

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(S)-(+)-2-Methylpiperazine is a valuable synthon for the synthesis of quinoline antibacterials and is utilized in asymmetric synthesis and heterocyclic building block applications.

What is the CAS number and chemical formula for (S)-(+)-2-Methylpiperazine?

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The CAS number for (S)-(+)-2-Methylpiperazine is 74879-18-8, and its chemical formula is C5H12N2.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies (S)-(+)-2-Methylpiperazine with an assay of 99%. This product is supplied for research and chemical synthesis purposes and is not represented as USP, BP, EP, or any other pharmacopoeia grade.

How should (S)-(+)-2-Methylpiperazine be handled safely?

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(S)-(+)-2-Methylpiperazine is a flammable solid (H228) and an irritant (H315, H319, H335). Handle with appropriate personal protective equipment, including eye shields, gloves, and respiratory protection (e.g., N95 dust mask or P3 filter), in a well-ventilated area, keeping away from ignition sources.

How is (S)-(+)-2-Methylpiperazine packed and shipped?

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Products are carefully packed according to international shipping regulations. Tech Serve Solutions is a global supplier and exporter, experienced in handling and shipping fine chemicals worldwide.

How can I request a sample or quote for (S)-(+)-2-Methylpiperazine?

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To request a sample or a quotation, please contact our sales team through the website or by phone, providing your details and the required quantity.

Need (S)-(+)-2-Methylpiperazine in a specific grade or volume?