(S)-(−)-1-Boc-3-acetamidopyrrolidine

CAS 114636-37-2C11H20N2O3Chemical Synthesis

(S)-(−)-1-Boc-3-acetamidopyrrolidine (CAS: 114636-37-2, C11H20N2O3) is a chiral building block with a molecular weight of 228.29 g/mol. This pyrrolidine derivative is primarily utilised in asymmetric synthesis and complex chemical synthesis pathways. Its specific stereochemistry makes it valuable for constructing chiral molecules and intermediates, particularly within pharmaceutical and fine chemical research and development.

IUPAC: tert-Butyl (3S)-3-(acetylamino)-1-pyrrolidinecarboxylate

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(S)-(−)-1-Boc-3-acetamidopyrrolidine (C11H20N2O3) — chemical structure, CAS 114636-37-2; Chemistry, fine chemical supplied by Tech Serve Solutions

Asymmetric SynthesisChemical SynthesisChiral Building BlocksHeterocyclic Building BlocksPyrrolidines

01 /Applications

Asymmetric Synthesis

Serves as a crucial chiral auxiliary or building block in enantioselective synthesis, enabling the formation of specific stereoisomers in complex molecules.

Pharmaceutical Intermediate Synthesis

Incorporated into synthetic routes for developing novel active pharmaceutical ingredients (APIs) and complex heterocyclic drug candidates.

Chiral Resolution Agent

Can be employed in the resolution of racemic mixtures, facilitating the separation of enantiomers.

Organic Synthesis

A versatile pyrrolidine derivative for general organic synthesis, offering a protected amino-alcohol functionality for further chemical modification.

02 /Properties

Molecular weight	228.29
Empirical formula	C11H20N2O3
Assay	97%
Optical activity	[α]20/D -18°, c = 3.5 in methanol
Storage temperature	2-8°C
Melting point	86-90 °C

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust, fume, gas or vapours
P305IF IN EYES

Protective equipment	dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Water hazard class (WGK, DE)	2
Hazard codes (EU)	Xn
Risk statements (R)	22-36/37/38
Safety statements (S)	26

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

114636-37-2

MDL number

MFCD08704350

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (S)-(−)-1-Boc-3-acetamidopyrrolidine primarily used for?

This compound is primarily used in asymmetric synthesis and the chemical synthesis of complex molecules, particularly as a chiral building block.

What is the CAS number and molecular formula for (S)-(−)-1-Boc-3-acetamidopyrrolidine?

The CAS number is 114636-37-2, and the molecular formula is C11H20N2O3.

What grade and purity does Tech Serve Solutions supply for (S)-(−)-1-Boc-3-acetamidopyrrolidine?

Tech Serve Solutions supplies this product with an assay of 97%. We do not represent it as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated in the product data.

How should (S)-(−)-1-Boc-3-acetamidopyrrolidine be handled safely?

This compound is classified as harmful if swallowed and causes skin, eye, and respiratory irritation (H302-H315-H319-H335). Use appropriate personal protective equipment including a dust mask (N95), eyeshields, face shields, and gloves. Ensure adequate ventilation.