(S)-(−)-1-Cbz-2-piperidinecarboxylic acid
(S)-(−)-1-Cbz-2-piperidinecarboxylic acid (CAS: 28697-11-2; Formula: C14H17NO4; MW: 263.29) is a chiral building block essential for asymmetric synthesis and complex chemical constructions. This N-protected piperidine derivative is widely employed in the synthesis of pharmaceuticals and advanced organic molecules. Its specific stereochemistry makes it valuable for developing stereospecific compounds, serving as a key intermediate in the creation of sophisticated chemical entities. Supplied by Tech Serve Solutions for research and development applications.
Chiral Synthesis
Serves as a crucial chiral building block in asymmetric synthesis, enabling the stereoselective construction of complex organic molecules. Its defined stereochemistry is vital for creating enantiomerically pure compounds.
Pharmaceutical Intermediates
Used as an intermediate in the synthesis of active pharmaceutical ingredients (APIs). Its piperidine core is a common motif in many drug molecules, making this compound valuable for drug discovery and development.
Heterocyclic Chemistry
As a functionalised piperidine derivative, it is instrumental in the synthesis of diverse heterocyclic compounds. These structures are prevalent in many biologically active molecules.
Peptide and Amino Acid Mimicry
Its structure, derived from piperidine-2-carboxylic acid, allows for its use in creating non-natural amino acids or peptidomimetics. This is useful in designing molecules with altered biological stability or activity.
| Molecular weight | 263.29 |
|---|---|
| Empirical formula | C14H17NO4 |
| Assay | 97% |
| Optical activity | [α]22/D −59°, c = 2 in acetic acid |
| Melting point | 111-115 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(−)-1-Cbz-2-piperidinecarboxylic acid primarily used for?
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It is primarily used as a chiral building block in asymmetric synthesis and as an intermediate in the synthesis of pharmaceuticals and complex organic molecules.
What are the CAS number and formula for this compound?
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The CAS number is 28697-11-2, and the empirical formula is C14H17NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical with an assay of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should (S)-(−)-1-Cbz-2-piperidinecarboxylic acid be handled safely?
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Handle with appropriate personal protective equipment including a dust mask (type N95 US), eyeshields, and gloves. Avoid breathing dust. Ensure adequate ventilation. This compound may cause skin and eye irritation and respiratory tract irritation (H315-H319-H335).
Is this chemical shipped internationally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals and laboratory reagents.
How can I request a sample or quote?
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Please contact our sales team directly through the website to request a sample or a quotation for (S)-(−)-1-Cbz-2-piperidinecarboxylic acid.
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