(S)-(−)-1-Methyl-2-pyrrolidinemethanol
(S)-(−)-1-Methyl-2-pyrrolidinemethanol (CAS: 34381-71-0, C6H13NO) is a chiral amino alcohol supplied by Tech Serve Solutions. With a molecular weight of 115.17 g/mol, this compound serves as a valuable precursor in chemical synthesis, particularly for the development of phosphine ligands used in catalytic asymmetric reactions. It is an essential building block for researchers and manufacturers in fields requiring stereoselective transformations.
- IUPAC
- (S)-2-Hydroxymethyl-1-methylpyrrolidine,N-Methyl-L-prolinol
- Synonyms
- (S)-2-Hydroxymethyl-1-methylpyrrolidineN-Methyl-L-prolinol
Asymmetric Catalysis
Utilised as a precursor for chiral phosphine ligands, enabling stereoselective Grignard cross-coupling reactions. This is crucial for synthesising enantiomerically pure compounds in pharmaceuticals and fine chemicals.
Chiral Building Block
Serves as a versatile chiral synthon in organic synthesis, particularly in the construction of complex molecules where stereochemistry is critical. Its pyrrolidine structure is common in many biologically active compounds.
Research and Development
An important reagent for academic and industrial R&D, facilitating studies in stereoselective synthesis, medicinal chemistry, and materials science. It aids in exploring new catalytic systems and synthetic methodologies.
| Molecular weight | 115.17 |
|---|---|
| Empirical formula | C6H13NO |
| Assay | 96% |
| Boiling point | 67-69 °C/12 mmHg(lit.) |
| Density | 0.968 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.469(lit.) |
| Optical activity | [α]19/D −49.5°, c = 5 in methanol |
| Application | Precursor to phosphine ligands for catalytic asymmetric Grignard cross-coupling reactions.1 |
| Protective equipment | Eyeshields, Gloves, half-mask respirator (EU), half-mask respirator (US), multi-purpose combination respirator cartridge (US) |
|---|---|
| Flash point | 63 °C / 145.4 °F |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(−)-1-Methyl-2-pyrrolidinemethanol used for?
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It is primarily used as a precursor for phosphine ligands in catalytic asymmetric Grignard cross-coupling reactions and as a chiral building block in organic synthesis.
What is the CAS number and molecular formula?
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The CAS number is 34381-71-0, and the molecular formula is C6H13NO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product at a purity of 96%. We do not represent this product as USP, BP, or EP grade unless explicitly stated.
How should (S)-(−)-1-Methyl-2-pyrrolidinemethanol be handled safely?
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Handle with appropriate personal protective equipment, including eyeshields and gloves. Ensure adequate ventilation; a half-mask respirator may be necessary. Refer to the safety data sheet for full handling instructions.
Is this chemical suitable for pharmaceutical manufacturing?
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While it is a precursor for reactions relevant to pharmaceutical synthesis, its stated purity of 96% indicates it is typically used for research and development or as a chemical intermediate rather than a direct active pharmaceutical ingredient (API) unless further purified and qualified.
How can I request a sample or quote?
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Please contact our sales team via the website or phone to request a sample or a quotation for (S)-(−)-1-Methyl-2-pyrrolidinemethanol.
Is this compound exported globally by TSS?
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Yes, Tech Serve Solutions specialises in the global supply and export of fine chemicals, including (S)-(−)-1-Methyl-2-pyrrolidinemethanol.
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