Rosiglitazone
Rosiglitazone (CAS: 122320-73-4), with the molecular formula C18H19N3O3S and a molecular weight of 357.43 g/mol, is a thiazolidinedione derivative. It functions as an agonist for peroxisome proliferator-activated receptor gamma (PPARγ). This compound is primarily investigated for its role in cellular metabolism and signalling pathways. Available as a powder, it is supplied by Tech Serve Solutions for research and development purposes.
- IUPAC
- 5-[[4-[2-(Methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-2,4-thiazolidinedione,Rosiglitazone
PPARγ Agonist Research
Rosiglitazone serves as a selective PPARγ agonist, widely used in biochemical and cellular research to investigate insulin sensitisation pathways. Its mechanism involves regulating genes involved in glucose and lipid metabolism.
Cell Signalling Studies
This compound is instrumental in studying cell signalling cascades related to metabolic control and inflammation. It aids researchers in understanding the complex interplay of nuclear receptors and gene expression.
Drug Discovery and Development
As a well-characterised molecule, Rosiglitazone is utilised in preclinical drug discovery programs targeting metabolic disorders. It provides a reference compound for the development of novel therapeutic agents.
| Molecular weight | 357.43 |
|---|---|
| Linear formula | C18H19N3O3S |
| Assay | ≥98% (HPLC)≥98% (HPLC) |
| Form | powder |
| Solubility | DMSO: ≥10 mg/mL |
| Storage temperature | 2-8°C |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Rosiglitazone used for?
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Rosiglitazone is used in research settings as a PPARγ agonist to study metabolic pathways, cell signalling, and in preclinical drug discovery for metabolic disorders.
What is the CAS number and molecular formula for Rosiglitazone?
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The CAS number for Rosiglitazone is 122320-73-4, and its molecular formula is C18H19N3O3S.
What grade and purity does Tech Serve Solutions supply for Rosiglitazone?
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Tech Serve Solutions supplies Rosiglitazone with a purity of ≥98% (HPLC). It is supplied for research purposes and is not represented as USP, BP, or EP grade.
How should Rosiglitazone be handled and stored?
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Rosiglitazone is classified with WGK Germany 3, indicating it is hazardous. It should be handled with appropriate personal protective equipment and stored at 2-8°C. Consult the Safety Data Sheet for detailed handling instructions.
Is Rosiglitazone a controlled substance?
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The provided data does not indicate that Rosiglitazone is a controlled substance.
How can I request a sample or quote for Rosiglitazone?
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To request a sample or quote for Rosiglitazone, please contact the Tech Serve Solutions sales team through our website or by phone.
How is Rosiglitazone packed, shipped, and exported?
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Rosiglitazone is typically supplied as a powder. Tech Serve Solutions handles packing, shipping, and export in accordance with all relevant regulations for chemical compounds.
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