(R)-Tetrahydrofuran-2-carbonitrile
(R)-Tetrahydrofuran-2-carbonitrile (CAS: 164472-78-0, C5H7NO) is a chiral building block with a molecular weight of 97.12 g/mol. This furan derivative is valuable in asymmetric synthesis and chemical research. It is supplied by Tech Serve Solutions with an assay of ≥98.0% (sum of enantiomers) and excellent optical purity (enantiomeric ratio ≥99:1), making it suitable for demanding synthetic applications in pharmaceutical and fine chemical development.
- IUPAC
- (R)-Tetrahydrofuroic nitrile,(R)-Tetrahydrofurfurylnitrile
Asymmetric Synthesis
Serves as a key chiral intermediate in the stereoselective synthesis of complex organic molecules, particularly pharmaceuticals and agrochemicals where specific enantiomers are critical.
Chiral Building Block
Provides a tetrahydrofuran core with a nitrile functional group, offering versatility for various transformations in organic synthesis to create enantiomerically pure compounds.
Heterocyclic Chemistry
Used in the development of novel heterocyclic compounds due to its furan ring structure, enabling the exploration of new chemical entities with potential biological activity.
Research and Development
Employed in academic and industrial research laboratories for method development, target molecule synthesis, and exploring new synthetic pathways.
| Molecular weight | 97.12 |
|---|---|
| Empirical formula | C5H7NO |
| Assay | ≥98.0% (sum of enantiomers, GC) |
| Optical purity | enantiomeric ratio: ≥99:1 (GC) |
Hazard statements
- H225Highly flammable liquid and vapour
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | -17 °C / 1.4 °F |
| Transport (UN / ADR) | UN 3273 3/PG 2 |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-20/21/22-36/37/38 |
| Safety statements (S) | 16-26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-Tetrahydrofuran-2-carbonitrile used for?
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(R)-Tetrahydrofuran-2-carbonitrile is primarily used as a chiral building block in asymmetric synthesis and for the development of novel heterocyclic compounds in chemical research and development.
What is the CAS number and formula for (R)-Tetrahydrofuran-2-carbonitrile?
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The CAS number is 164472-78-0 and the empirical formula (Hill notation) is C5H7NO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-Tetrahydrofuran-2-carbonitrile with an assay of ≥98.0% (sum of enantiomers, GC) and an enantiomeric ratio of ≥99:1 (GC). We do not represent this product as USP, BP, or EP grade.
How should (R)-Tetrahydrofuran-2-carbonitrile be handled safely?
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This compound is flammable (Flash Point: -17 °C) and harmful if swallowed, inhaled, or in contact with skin. It also causes skin, eye, and respiratory irritation. Handle with appropriate personal protective equipment, including safety eyeshields, gloves, and a suitable respirator, in a well-ventilated area, away from ignition sources.
Is (R)-Tetrahydrofuran-2-carbonitrile regulated?
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The provided data does not indicate that (R)-Tetrahydrofuran-2-carbonitrile is a controlled substance. Please refer to local regulations for specific requirements.
How is this chemical exported and shipped?
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(R)-Tetrahydrofuran-2-carbonitrile is classified under UN 3273, Hazard Class 3, Packing Group II, indicating it is a flammable liquid. TSS ensures compliance with all international shipping and export regulations for hazardous materials.
How can I request a sample or a quote?
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To request a sample or obtain a quotation for (R)-Tetrahydrofuran-2-carbonitrile, please contact our sales team through the website or by direct inquiry, providing your specific requirements.
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