(R)-ShiP
(R)-ShiP, CAS 656233-53-3, is a phosphite ligand with the empirical formula C23H19O3P and a molecular weight of 374.37 g/mol. It is primarily utilised as a chiral catalyst in asymmetric synthesis, facilitating the stereoselective creation of complex molecules. This compound is crucial for researchers and manufacturers involved in fine chemical synthesis and pharmaceutical intermediate production requiring precise enantiomeric control.
- IUPAC
- (11aR)-(+)-10,11,12,13-Tetrahydrodiindeno[7,1-de:1′,7′-fg][1,3,2]dioxaphosphocin-5-phenoxy,Phenyl-[(R)-1,1-spirobiindane-7,7-diyl]-phosphite
Asymmetric Catalysis
(R)-ShiP serves as a key chiral ligand in transition metal-catalyzed asymmetric reactions. Its structure enables high enantioselectivity in various transformations, vital for producing enantiomerically pure compounds.
Pharmaceutical Intermediate Synthesis
This compound is employed in the synthesis of complex chiral building blocks for active pharmaceutical ingredients (APIs). Its application ensures the stereochemical integrity required in drug development and manufacturing.
Fine Chemical Production
In the fine chemical sector, (R)-ShiP facilitates the stereoselective synthesis of high-value molecules. It is instrumental in processes where specific stereoisomers are required for their functional properties.
| Molecular weight | 374.37 |
|---|---|
| Empirical formula | C23H19O3P |
| Assay | 97% |
| Optical activity | [α]22/D +209°, c = 1 in chloroform |
| Melting point | 91-105 °C |
Hazard statements
- H302Harmful if swallowed
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-ShiP used for?
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(R)-ShiP is primarily used as a chiral ligand in asymmetric synthesis and for the production of pharmaceutical intermediates and fine chemicals where stereoselectivity is critical.
What are the CAS number and formula for (R)-ShiP?
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The CAS number for (R)-ShiP is 656233-53-3, and its empirical formula is C23H19O3P.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-ShiP with a minimum assay of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety precautions for handling (R)-ShiP?
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Handling (R)-ShiP requires appropriate personal protective equipment, including a dust mask (type N95 or equivalent), eyeshields, and gloves. The compound is classified as harmful if swallowed (H302).
How is (R)-ShiP packed and shipped?
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Tech Serve Solutions professionally packs and exports fine chemicals like (R)-ShiP globally, adhering to all necessary shipping regulations for hazardous materials.
How can I request a sample or quote for (R)-ShiP?
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To request a sample or obtain a quote for (R)-ShiP, please contact our sales team through the website or via email, providing your specific requirements.
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