2′,4′,5′-Trifluoroacetophenone
2′,4′,5′-Trifluoroacetophenone (CAS: 129322-83-4) is a fluorinated organic compound with the molecular formula F₃C₆H₂COCH₃ and a molecular weight of 174.12 g/mol. It serves as a valuable building block in organic synthesis. This ketone features a trifluorinated phenyl ring, making it useful for introducing fluorinated moieties into more complex molecular structures. It is primarily utilised in research and development settings for the synthesis of novel compounds.
- Synonyms
- 129322-83-4F3C6H2COCH3

Fluorinated Intermediate in Synthesis
2′,4′,5′-Trifluoroacetophenone acts as a key intermediate for the synthesis of complex fluorinated organic molecules. Its trifluorophenyl group can be further functionalised to create diverse chemical structures.
Building Block for Specialty Chemicals
This compound is employed as a building block in the development of specialty chemicals, particularly where fluorine incorporation is desired to modulate physical or biological properties.
Research and Development
Its specific structural features make it a compound of interest for academic and industrial research laboratories exploring new synthetic routes and novel chemical entities.
| Molecular weight | 174.12 |
|---|---|
| Linear formula | F3C6H2COCH3 |
| Assay | 99% |
| Density | 1.331 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.472(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 71 °C / 159.8 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2′,4′,5′-Trifluoroacetophenone used for?
+
2′,4′,5′-Trifluoroacetophenone is primarily used as a building block and intermediate in organic synthesis, particularly for creating more complex fluorinated organic molecules in research and development settings.
What is the CAS number and molecular formula for 2′,4′,5′-Trifluoroacetophenone?
+
The CAS number is 129322-83-4 and the molecular formula is F₃C₆H₂COCH₃.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 2′,4′,5′-Trifluoroacetophenone with a purity of 99% assay. We do not represent this product as USP, BP, EP, or other pharmacopoeial grades.
How should 2′,4′,5′-Trifluoroacetophenone be handled?
+
2′,4′,5′-Trifluoroacetophenone is a Warning substance that can cause skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including eyeshields, gloves, and suitable respiratory protection, should be used. Avoid breathing dust/fume/gas/mist/vapours/spray and ensure adequate ventilation.
Is 2′,4′,5′-Trifluoroacetophenone a controlled substance?
+
The provided data does not indicate that 2′,4′,5′-Trifluoroacetophenone is a controlled substance.
How is this chemical packed, shipped, and exported?
+
As a global supplier, Tech Serve Solutions adheres to all relevant regulations for packing, shipping, and exporting chemicals worldwide. Specific packaging details will be provided with your order.
How can I request a sample or quote for 2′,4′,5′-Trifluoroacetophenone?
+
To request a sample or a quote, please contact our sales team through the website or by calling us directly. Please reference the product name and CAS number.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis