(R)-Tetrahydro-3-furoic acid
(R)-Tetrahydro-3-furoic acid (CAS: 66838-42-4) is a chiral building block used in asymmetric synthesis and general chemical synthesis. This furan derivative offers a specific stereochemical configuration, making it valuable for constructing complex molecules with defined spatial arrangements. It is primarily utilised in research and development settings for the creation of novel compounds, particularly within pharmaceutical and fine chemical industries. Its heterocyclic structure and chirality are key features for its synthetic utility.
- IUPAC
- (R)-Tetrahydro-3-furancarboxylic acid
- Synonyms
- (R)-Tetrahydro-3-furancarboxylic acid

Chiral Building Block
(R)-Tetrahydro-3-furoic acid serves as a crucial chiral synthon in the construction of enantiomerically pure compounds. Its defined stereochemistry allows for the introduction of specific chirality into target molecules during multi-step synthesis.
Asymmetric Synthesis
This compound is employed in asymmetric synthesis to achieve stereoselective reactions. It can be a starting material or intermediate for creating complex chiral molecules where precise spatial orientation is critical.
Pharmaceutical Intermediate
As a valuable intermediate, it can be used in the research and development of new pharmaceutical agents. Its furan ring and chiral centre are structural motifs found in various biologically active molecules.
Fine Chemical Synthesis
It finds application in the broader field of fine chemical synthesis, enabling the production of specialised chemicals with unique structural properties for diverse industrial needs.
| Assay | ≥97.0% (GC)≥97.0%97.0-103.0% (T) |
|---|---|
| Optical purity | enantiomeric excess: ≥95.0% |

Hazard statements
- H319Causes serious eye irritation
Precautionary statements
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-Tetrahydro-3-furoic acid used for?
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(R)-Tetrahydro-3-furoic acid is primarily used as a chiral building block in asymmetric synthesis and chemical synthesis, often serving as an intermediate in the development of pharmaceuticals and fine chemicals.
What is the CAS number and formula for (R)-Tetrahydro-3-furoic acid?
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The CAS number for (R)-Tetrahydro-3-furoic acid is 66838-42-4. The molecular formula is not provided in the data, but the structure corresponds to C5H8O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-Tetrahydro-3-furoic acid with an assay of ≥97.0% (GC) or ≥97.0% (T), and an enantiomeric excess of ≥95.0%. We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should (R)-Tetrahydro-3-furoic acid be handled?
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According to GHS classification, (R)-Tetrahydro-3-furoic acid is classified with Warning (H319), indicating it causes serious eye irritation. It is advised to wear eye protection (P305 + P351 + P338) and if in eyes, rinse cautiously with water for several minutes.
Is (R)-Tetrahydro-3-furoic acid a controlled substance?
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The provided data does not indicate that (R)-Tetrahydro-3-furoic acid is a controlled substance.
How is this chemical packed, shipped, and exported?
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Tech Serve Solutions, as a specialist global supplier and exporter since 1998, ensures appropriate packaging for shipment and export of (R)-Tetrahydro-3-furoic acid, adhering to international regulations.
How can I request a sample or quote for (R)-Tetrahydro-3-furoic acid?
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You can request a sample or obtain a quote for (R)-Tetrahydro-3-furoic acid by contacting our sales team through the dedicated channels on the Tech Serve Solutions website.
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