4-Nitrophthalic anhydride
4-Nitrophthalic anhydride (CAS: 5466-84-2, Formula: C8H3NO5) is a dicarboxylic anhydride with a molecular weight of 193.11 g/mol. This compound serves as a valuable intermediate in organic synthesis, particularly in the development of polymers and advanced materials. Its nitro group offers a site for further chemical modification, making it a versatile building block for specialised chemical research and development projects.

Polymer Science Intermediate
4-Nitrophthalic anhydride can be used as a monomer or co-monomer in the synthesis of various polymers. Its structure allows for incorporation into polymer backbones, potentially imparting unique thermal or electronic properties.
Organic Synthesis Building Block
The compound's anhydride functionality reacts readily with nucleophiles, while the nitro group can be reduced or otherwise transformed, making it a versatile intermediate for creating complex organic molecules.
Materials Science Research
It serves as a precursor in the development of novel materials, including functional dyes, pigments, and specialty resins where specific electronic or structural characteristics are desired.
| Molecular weight | 193.11 |
|---|---|
| Empirical formula | C8H3NO5 |
| Assay | 92% |
| Impurities tested | 5-8% 3-nitrophthalic anhydride |
| Melting point | 116-120 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Nitrophthalic anhydride used for?
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4-Nitrophthalic anhydride is primarily used as an intermediate in organic synthesis, particularly in polymer science and materials science for developing specialised compounds and materials.
What are the CAS number and formula for 4-Nitrophthalic anhydride?
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The CAS number is 5466-84-2 and the empirical formula is C8H3NO5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Nitrophthalic anhydride with an assay of 92%, containing 5-8% 3-nitrophthalic anhydride impurities. It is supplied as a technical/research grade and is not represented as USP, BP, or EP.
How should 4-Nitrophthalic anhydride be handled?
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Handle with appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves. Avoid breathing dust and ensure adequate ventilation. This compound is classified under GHS07 with the signal word 'Warning' and has hazard statements H315, H319, and H335, indicating it causes skin irritation, serious eye irritation, and may cause respiratory irritation.
Is 4-Nitrophthalic anhydride a controlled substance?
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The provided data does not indicate that 4-Nitrophthalic anhydride is a controlled substance.
How is 4-Nitrophthalic anhydride packed and shipped?
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Tech Serve Solutions exports fine chemicals globally. Specific packing and shipping details for 4-Nitrophthalic anhydride will be provided upon inquiry, adhering to international shipping regulations.
How can I request a quote or sample for 4-Nitrophthalic anhydride?
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To request a quote or sample of 4-Nitrophthalic anhydride, please contact our sales department through the website or by phone, providing your contact details and the required quantity.
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