5-Bromo-2-(trifluoromethyl)pyridine
5-Bromo-2-(trifluoromethyl)pyridine (CAS 436799-32-5, C6H3BrF3N) is a halogenated heterocyclic building block with a molecular weight of 225.99 g/mol. Supplied by Tech Serve Solutions with an assay of 97%, this compound serves as a valuable intermediate in organic synthesis. Its specific reactivity allows for regioselective functionalization, making it a key component in the development of complex molecules for research and chemical applications.
Organic Synthesis Intermediate
Utilised as a building block in the synthesis of more complex organic molecules. Its structure, featuring both a bromine atom and a trifluoromethyl group on a pyridine ring, offers unique reactivity for chemical transformations.
Regioselective Functionalization
Enables regioselective C-4 deprotonation, followed by trapping with carbon dioxide, to yield the corresponding C-4 acid. This specific reaction pathway is crucial for targeted molecular construction in advanced synthesis.
Heterocyclic Chemistry
As a substituted pyridine, it is integral to research and development within heterocyclic chemistry, contributing to the creation of novel compounds with potential applications in various scientific fields.
| Molecular weight | 225.99 |
|---|---|
| Empirical formula | C6H3BrF3N |
| Assay | 97% |
| Application | Regioselective C-4 deprotonation with LDA and trapping with carbon dioxide leads to the corresponding C-4 acid.1 |
| Melting point | 41-45 °C |
Hazard statements
- H301Toxic if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Flash point | 78 °C / 172.4 °F |
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25-36/37/38 |
| Safety statements (S) | 26-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Bromo-2-(trifluoromethyl)pyridine used for?
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5-Bromo-2-(trifluoromethyl)pyridine is primarily used as a building block in organic synthesis, particularly for regioselective functionalization and in heterocyclic chemistry research.
What are the CAS number and molecular formula for 5-Bromo-2-(trifluoromethyl)pyridine?
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The CAS number is 436799-32-5, and the molecular formula is C6H3BrF3N.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-Bromo-2-(trifluoromethyl)pyridine with an assay of 97%. TSS does not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should 5-Bromo-2-(trifluoromethyl)pyridine be handled safely?
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This compound is classified as Danger (GHS06) and is toxic if swallowed (H301), causes skin irritation (H315), causes serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment, including eyeshields, face shields, gloves, and P2 respirator cartridges, in a well-ventilated area.
How is 5-Bromo-2-(trifluoromethyl)pyridine packed, shipped, and exported?
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5-Bromo-2-(trifluoromethyl)pyridine is shipped according to UN 2811 6.1 / PGIII regulations. TSS is a specialist global supplier and exporter of fine chemicals.
How can I request a quote or sample?
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Please contact our sales team via the website to request a quote or to discuss obtaining a sample of 5-Bromo-2-(trifluoromethyl)pyridine.
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