5-Bromo-2-(tert-butyldimethylsiloxy)pyrimidine
5-Bromo-2-(tert-butyldimethylsiloxy)pyrimidine (CAS: 121519-00-4), with molecular formula C10H17BrN2OSi and a molecular weight of 289.24 g/mol, is a valuable heterocyclic building block. It features a pyrimidine core functionalised with a bromine atom and a silyl-protected hydroxyl group. This compound is primarily utilised in organic synthesis, particularly in the development of novel pharmaceutical intermediates and complex molecules requiring precise structural modifications.
Organic Synthesis Intermediate
Serves as a versatile building block in multi-step organic syntheses. The bromine atom and the protected hydroxyl group allow for selective functionalisation and coupling reactions.
Pharmaceutical Research
Facilitates the construction of biologically active compounds and pharmaceutical intermediates. Its structure is amenable to modifications for drug discovery programs.
Heterocyclic Chemistry
A key reagent for introducing the pyrimidine moiety into more complex heterocyclic systems. Useful in the synthesis of novel compounds with potential material science applications.
| Molecular weight | 289.24 |
|---|---|
| Empirical formula | C10H17BrN2OSi |
| Assay | 97% |
| Refractive index | n20/D 1.509(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | >110 °C / >230 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Bromo-2-(tert-butyldimethylsiloxy)pyrimidine used for?
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This compound is primarily used as a building block in organic synthesis, particularly in the development of pharmaceutical intermediates and complex heterocyclic molecules.
What are the CAS number and molecular formula?
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The CAS number is 121519-00-4, and the molecular formula is C10H17BrN2OSi.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical with an assay of 97%. We do not represent this product as meeting USP, BP, EP, or any other pharmacopoeial standards.
How should this chemical be handled safely?
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This compound is classified with GHS07 signal word 'Warning' and hazard statements H315, H319, H335, indicating it causes skin irritation, serious eye irritation, and may cause respiratory irritation. Always use appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, in a well-ventilated area. Avoid breathing dust/fume/gas/mist/vapours/spray.
Is this chemical a controlled substance?
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The provided data does not indicate that this chemical is a controlled substance.
How is this product typically packed and shipped?
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Products are packed and shipped according to standard chemical handling regulations to ensure safe transport, fulfilling export requirements.
How can I request a sample or quote?
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To request a sample or quote, please contact our sales team through the website or by calling us directly. Please reference the product name and CAS number.
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