(R)-(+)-4-Chloromandelonitrile
(R)-(+)-4-Chloromandelonitrile (CAS: 97070-79-6), a chiral organic compound with the formula ClC6H4CH(OH)CN and a molecular weight of 167.59 g/mol, serves as a valuable intermediate. Its primary utility lies in the synthesis of optically active α-hydroxy carboxylic acids, α-hydroxy aldehydes, α-hydroxy ketones, and 2-amino alcohols. Available at 97% purity, it is supplied by Tech Serve Solutions for various chemical synthesis applications.
Synthesis of Optically Active Hydroxy Compounds
This chiral building block is instrumental in preparing optically active α-hydroxy carboxylic acids, aldehydes, and ketones, enabling the synthesis of complex chiral molecules.
Preparation of Chiral Amino Alcohols
(R)-(+)-4-Chloromandelonitrile is a key intermediate for the synthesis of chiral 2-amino alcohols, which are important motifs in pharmaceuticals and asymmetric catalysis.
Asymmetric Synthesis Intermediate
As a readily available chiral nitrile, it facilitates stereoselective transformations, contributing to the field of asymmetric synthesis in organic chemistry.
| Molecular weight | 167.59 |
|---|---|
| Linear formula | ClC6H4CH(OH)CN |
| Assay | 97% |
| Optical activity | [α]20/D +39°, c = 1 in chloroform |
| Storage temperature | 2-8°C |
| Application | Useful intermediate in the preparation of optically active α-hydroxy carboxylic acids, α-hydroxy aldehydes, α-hydroxy ketones, and 2-amino alcohols.1 |
| Melting point | 70-74 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H332Harmful if inhaled
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22 |
| Safety statements (S) | 36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(+)-4-Chloromandelonitrile used for?
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(R)-(+)-4-Chloromandelonitrile is primarily used as an intermediate in the preparation of optically active α-hydroxy carboxylic acids, α-hydroxy aldehydes, α-hydroxy ketones, and 2-amino alcohols.
What is the CAS number and chemical formula for (R)-(+)-4-Chloromandelonitrile?
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The CAS number is 97070-79-6, and the chemical formula is ClC6H4CH(OH)CN.
What grade and purity does Tech Serve Solutions supply for (R)-(+)-4-Chloromandelonitrile?
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Tech Serve Solutions supplies (R)-(+)-4-Chloromandelonitrile with a purity of 97%. We do not represent this product as USP, BP, or EP grade.
What are the safety and handling considerations for (R)-(+)-4-Chloromandelonitrile?
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(R)-(+)-4-Chloromandelonitrile is classified as harmful if swallowed, in contact with skin, or if inhaled (H302-H312-H332). Appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves, should be used. Handle in a well-ventilated area.
How is (R)-(+)-4-Chloromandelonitrile typically stored and shipped?
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This compound is typically stored at 2-8°C. TSS exports chemicals globally, adhering to all necessary regulations for safe transport.
How can I request a quote or sample of (R)-(+)-4-Chloromandelonitrile?
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To request a quote or sample, please contact the Tech Serve Solutions sales team via our website or direct inquiry channels.
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