(R)-(+)-4-(Methoxymethyl)-1,3-dioxolan-2-one
(R)-(+)-4-(Methoxymethyl)-1,3-dioxolan-2-one (CAS: 185836-34-4) is a chiral organic building block with the molecular formula C5H8O4 and a molecular weight of 132.11 g/mol. It is primarily employed in asymmetric synthesis and chemical manufacturing. This compound serves as a valuable intermediate for creating complex chiral molecules, offering a stereochemically defined starting point for various synthetic routes. Its availability from Tech Serve Solutions supports research and development in pharmaceuticals and fine chemicals.
- IUPAC
- (R)-3-Methoxy-1,2-propanediol cyclic carbonate
- Synonyms
- (R)-3-Methoxy-1,2-propanediol cyclic carbonate

Asymmetric Synthesis
Utilised as a chiral building block in stereoselective synthesis to construct enantiomerically pure compounds. Its defined stereochemistry is crucial for developing chiral drugs and other optically active molecules.
Pharmaceutical Intermediates
Serves as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs) where chirality is essential for biological activity and efficacy. Facilitates the creation of complex molecular architectures.
Organic Synthesis
A versatile reagent in general organic synthesis, enabling the introduction of specific functional groups and chiral centres. Its cyclic carbonate structure offers unique reactivity for various transformations.
| Molecular weight | 132.11 |
|---|---|
| Empirical formula | C5H8O4 |
| Assay | 98% |
| Boiling point | 105-106 °C/0.9 mmHg(lit.) |
| Density | 1.24 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.437(lit.) |
| Optical activity | [α]20/D +44°, neat |
| Optical purity | ee: 97% (GLC) |
| Flash point | 113 °C / 235.4 °F |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(+)-4-(Methoxymethyl)-1,3-dioxolan-2-one used for?
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This compound is primarily used in asymmetric synthesis and as a chiral building block in the preparation of pharmaceutical intermediates and other complex organic molecules.
What are the CAS number and formula for (R)-(+)-4-(Methoxymethyl)-1,3-dioxolan-2-one?
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The CAS number is 185836-34-4, and its molecular formula is C5H8O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-(+)-4-(Methoxymethyl)-1,3-dioxolan-2-one with an assay of 98%. This is a technical/research grade material, and TSS does not represent it as USP, BP, or EP grade.
What are the safety and handling considerations for this chemical?
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This compound has a flash point of 113 °C (235.4 °F) and is classified under WGK Germany 3. Handle with appropriate personal protective equipment in a well-ventilated area, avoiding exposure to heat and ignition sources.
How is this product packed, shipped, and exported?
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Tech Serve Solutions offers this product in various pack sizes suitable for laboratory and industrial use, adhering to all necessary regulations for domestic and international shipping and export.
How can I request a sample or a quote for (R)-(+)-4-(Methoxymethyl)-1,3-dioxolan-2-one?
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To request a sample or a quote, please contact our sales team through the website or by phone, providing your specific requirements and contact details.
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