(R)-(+)-4-Benzyl-5,5-dimethyl-2-oxazolidinone
(R)-(+)-4-Benzyl-5,5-dimethyl-2-oxazolidinone (CAS 204851-73-0) is a chiral auxiliary with the molecular formula C12H15NO2 and a molecular weight of 205.25 g/mol. This compound is an essential tool in asymmetric synthesis, particularly for constructing complex organic molecules with high stereochemical control. Its robust structure and predictable reactivity make it a valuable reagent for diastereoselective reactions, enabling the efficient creation of enantiomerically enriched products.
- Synonyms
- C12H15NO2
Asymmetric Michael Additions
This oxazolidinone derivative serves as a versatile chiral auxiliary in diastereoselective Michael addition reactions. It effectively directs the stereochemical outcome of the addition, leading to the formation of enantiomerically enriched products with high fidelity.
Chiral Synthesis
As a key component in chiral synthesis, (R)-(+)-4-Benzyl-5,5-dimethyl-2-oxazolidinone facilitates the preparation of enantiomerically pure compounds. Its application is crucial in multi-step syntheses where precise stereochemical control is paramount.
Oxazolidinone Chemistry
Belonging to the family of oxazolidinone derivatives, this compound leverages the established reactivity patterns of this structural class. It is employed in various synthetic transformations requiring a reliable chiral directing group.
| Molecular weight | 205.25 |
|---|---|
| Empirical formula | C12H15NO2 |
| Assay | 98% |
| Optical activity | [α]20/D +96°, c = 2 in chloroform |
| Optical purity | ee: 99% (HPLC) |
| Application | Versatile chiral auxiliary for asymmetric synthesis used in diastereoselective Michael additions.1 |
| Melting point | 60-62 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(+)-4-Benzyl-5,5-dimethyl-2-oxazolidinone used for?
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This compound is primarily used as a versatile chiral auxiliary in asymmetric synthesis, particularly for diastereoselective Michael additions and other stereocontrolled transformations.
What are the CAS number and molecular formula for this compound?
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The CAS number is 204851-73-0, and the molecular formula is C12H15NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-(+)-4-Benzyl-5,5-dimethyl-2-oxazolidinone with an assay of 98%. We do not represent this product as USP, BP, or EP grade.
How should this chemical be handled safely?
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Handle with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves. Avoid breathing dust and ensure adequate ventilation, as it may cause skin, eye, and respiratory irritation (H315, H319, H335).
Is this chemical available for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals.
How can I request a sample or obtain a quote?
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Please contact our sales team or use the online portal to request a sample or obtain a quote for (R)-(+)-4-Benzyl-5,5-dimethyl-2-oxazolidinone.
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