(R)-(+)-4-Hydroxy-2-pyrrolidinone
(R)-(+)-4-Hydroxy-2-pyrrolidinone (CAS: 22677-21-0, C4H7NO2) is a chiral heterocyclic compound with a molecular weight of 101.10 g/mol. This optically active lactam, specifically the (R)-enantiomer, serves as a valuable building block in asymmetric synthesis. Its structure makes it suitable for constructing more complex chiral molecules, particularly in the fields of pharmaceuticals and fine chemicals. Tech Serve Solutions supplies this compound for research and development purposes.
- IUPAC
- (R)-β-Hydroxy-γ-butyrolactam
Chiral Building Block in Organic Synthesis
(R)-(+)-4-Hydroxy-2-pyrrolidinone is a key intermediate for the synthesis of enantiomerically pure compounds. Its defined stereochemistry allows for the introduction of chirality in target molecules, crucial for pharmaceutical development.
Asymmetric Synthesis Applications
This pyrrolidinone derivative is employed in asymmetric synthesis methodologies to create chiral centres with high enantioselectivity. It is valuable for researchers developing novel synthetic routes to complex organic molecules.
Heterocyclic Chemistry Research
As a functionalised heterocyclic compound, it finds use in exploring new chemical transformations and developing novel heterocyclic frameworks. Its applications span academic research and industrial R&D.
| Molecular weight | 101.10 |
|---|---|
| Empirical formula | C4H7NO2 |
| Assay | 97% |
| Optical activity | [α]23/D +43°, c = 1 in ethanol |
| Melting point | 156-159 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(+)-4-Hydroxy-2-pyrrolidinone used for?
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(R)-(+)-4-Hydroxy-2-pyrrolidinone is primarily used as a chiral building block in asymmetric synthesis and for the development of complex organic molecules in pharmaceutical and fine chemical research.
What are the CAS number and formula for (R)-(+)-4-Hydroxy-2-pyrrolidinone?
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The CAS number for (R)-(+)-4-Hydroxy-2-pyrrolidinone is 22677-21-0 and its empirical formula is C4H7NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-(+)-4-Hydroxy-2-pyrrolidinone with an assay of 97%. This product is intended for research and development; TSS does not represent it as USP, BP, or EP grade.
What are the safety and handling recommendations for (R)-(+)-4-Hydroxy-2-pyrrolidinone?
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This compound is classified as a Warning, with hazards including skin irritation (H315), eye irritation (H319), and respiratory irritation (H335). Recommended personal protective equipment includes a dust mask (type N95), eyeshields, and gloves. Handle in a well-ventilated area and avoid dust formation.
How is (R)-(+)-4-Hydroxy-2-pyrrolidinone packed and exported?
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(R)-(+)-4-Hydroxy-2-pyrrolidinone is carefully packed according to international shipping regulations for chemical substances and is available for global export.
How can I request a quote or sample for (R)-(+)-4-Hydroxy-2-pyrrolidinone?
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To request a quote or sample, please contact our sales team through the website or by direct enquiry, providing your contact details and the required quantity.
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