(R)-(+)-4-Isopropyl-5,5-dimethyl-2-oxazolidinone
(R)-(+)-4-Isopropyl-5,5-dimethyl-2-oxazolidinone (CAS: 223906-38-5) is a chiral auxiliary with the molecular formula C8H15NO2 and a molecular weight of 157.21 g/mol. This compound is a valuable tool in asymmetric synthesis, particularly recognised for its utility in diastereoselective Michael additions. Supplied by Tech Serve Solutions with a minimum assay of 98%, it is suitable for advanced chemical research and development requiring precise stereochemical control.
- Synonyms
- C8H15NO2
Asymmetric Synthesis
Serves as a versatile chiral auxiliary for the stereocontrolled synthesis of complex organic molecules. Its structure facilitates high diastereoselectivity in key carbon-carbon bond-forming reactions.
Diastereoselective Michael Additions
Effectively employed in conjugate addition reactions to introduce chirality. The oxazolidinone ring system directs the approach of nucleophiles, leading to enantiomerically enriched products.
Chiral Auxiliary
A key component in methodologies requiring the temporary incorporation of a chiral centre to influence the stereochemical outcome of a reaction.
| Molecular weight | 157.21 |
|---|---|
| Empirical formula | C8H15NO2 |
| Assay | 98% |
| Optical activity | [α]20/D +47°, c = 1 in H2O |
| Application | Versatile chiral auxiliary for asymmetric synthesis used in diastereoselective Michael additions.1 |
| Melting point | 86-87 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Flash point | 20 °C / 68 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xi |
| Risk statements (R) | 11-36/37/38 |
| Safety statements (S) | 16-26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(+)-4-Isopropyl-5,5-dimethyl-2-oxazolidinone used for?
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(R)-(+)-4-Isopropyl-5,5-dimethyl-2-oxazolidinone is used as a versatile chiral auxiliary in asymmetric synthesis, particularly for diastereoselective Michael additions, enabling the stereocontrolled formation of carbon-carbon bonds.
What is the CAS number and formula for (R)-(+)-4-Isopropyl-5,5-dimethyl-2-oxazolidinone?
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The CAS number is 223906-38-5 and the empirical formula (Hill notation) is C8H15NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-(+)-4-Isopropyl-5,5-dimethyl-2-oxazolidinone with a minimum assay of 98%. TSS does not represent this product as USP, BP, EP or other pharmacopoeial grades.
How should (R)-(+)-4-Isopropyl-5,5-dimethyl-2-oxazolidinone be handled?
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This compound is a Warning, indicated by GHS07. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, gloves, and suitable respirators, should be used. Handle in a well-ventilated area.
Can Tech Serve Solutions export this chemical?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals and laboratory reagents.
How can I request a sample or quote for this chemical?
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Please contact our sales team directly through our website or by phone to request a sample or a quotation for (R)-(+)-4-Isopropyl-5,5-dimethyl-2-oxazolidinone.
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