Ethyl fumaroyl chloride
Ethyl fumaroyl chloride (CAS: 26367-48-6), a derivative of fumaric acid with formula C6H7ClO3 and a molecular weight of 162.57 g/mol, is a reactive acid halide. It serves as a versatile building block in organic synthesis. Its primary utility lies in introducing the ethyl fumaroyl moiety into various organic structures, facilitating the creation of complex molecules for research and development purposes.
- IUPAC
- (E)-3-(Chloroformyl)-acrylic acid ethyl ester,Ethyl fumaryl chloride

Organic Synthesis Intermediate
Ethyl fumaroyl chloride functions as a key intermediate in the synthesis of diverse organic compounds. Its reactive acyl chloride group readily participates in esterification and amidation reactions, enabling the construction of more complex molecular frameworks.
Pharmaceutical Research
This compound can be employed in the development of novel pharmaceutical agents. Its structural features allow for incorporation into potential drug candidates, contributing to medicinal chemistry research efforts.
Materials Science
Ethyl fumaroyl chloride may find application in the synthesis of specialised polymers or functionalised materials. The introduction of its characteristic functional groups can impart specific properties to the resulting materials.
| Molecular weight | 162.57 |
|---|---|
| Empirical formula | C6H7ClO3 |
| Assay | ≥97.0% |
| Refractive index | n20/D 1.463 |



Hazard statements
- H302Harmful if swallowed
- H314Causes severe skin burns and eye damage
- H317May cause an allergic skin reaction
- H334May cause allergy or asthma symptoms if inhaled
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 22-34-43 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ethyl fumaroyl chloride used for?
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Ethyl fumaroyl chloride is primarily used as an intermediate in organic synthesis, particularly in the preparation of esters and amides, and in pharmaceutical and materials science research.
What are the CAS number and formula for Ethyl fumaroyl chloride?
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The CAS number for Ethyl fumaroyl chloride is 26367-48-6, and its molecular formula is C6H7ClO3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Ethyl fumaroyl chloride with an assay of ≥97.0%. This is a technical grade and is not represented as USP, BP, or EP.
How should Ethyl fumaroyl chloride be handled safely?
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Ethyl fumaroyl chloride is a Danger hazard, causing severe skin burns and eye damage (H314). It is harmful if swallowed (H302) and may cause allergy or asthma symptoms or breathing difficulties if inhaled (H334). It may cause an allergic skin reaction (H317). Always use appropriate personal protective equipment, including full-face respirators, gloves, and goggles, and ensure adequate ventilation when handling.
Is Ethyl fumaroyl chloride a controlled substance?
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The provided data does not indicate that Ethyl fumaroyl chloride is a controlled substance.
How is Ethyl fumaroyl chloride packed, shipped, and exported?
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Ethyl fumaroyl chloride is shipped as UN 3265, Class 8, Packing Group II. Tech Serve Solutions, as a specialist global supplier and exporter, handles its packaging and shipping in accordance with relevant transport regulations.
How can I request a quote or sample of Ethyl fumaroyl chloride?
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To request a quote or sample of Ethyl fumaroyl chloride, please contact our sales team through the provided channels on the Tech Serve Solutions website.
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