Pyridoxal 5′-phosphate hydrate
Pyridoxal 5′-phosphate hydrate (CAS 853645-22-4), with the empirical formula C8H10NO6P · xH2O and a molecular weight of 247.14 (anhydrous basis), is a hydrated form of pyridoxal 5′-phosphate. This compound serves as a vital coenzyme in numerous metabolic pathways, acting as an enzyme inhibitor in biochemical research. It is a key derivative of Vitamin B6, essential for amino acid metabolism and other enzymatic reactions.
- IUPAC
- 3-Hydroxy-2-methyl-5-([phosphonooxy]methyl)-4-pyridinecarboxaldehyde,Codecarboxylase,PLP,Pyridoxal 5-phosphate
- Synonyms
- 3-Hydroxy-2-methyl-5-([phosphonooxy]methyl)-4-pyridinecarboxaldehyde, Codecarboxylase, PLP, Pyridoxal 5-phosphate

Biochemical Research
Pyridoxal 5′-phosphate hydrate is utilised as an enzyme inhibitor in biochemical studies to investigate metabolic pathways and enzyme mechanisms. Its role as a derivative of Vitamin B6 makes it crucial for understanding amino acid metabolism.
Chemical Synthesis
As a heterocyclic building block, this compound can be employed in organic synthesis for the creation of more complex molecules. Its pyridine ring and functional groups offer versatile reaction sites for synthetic chemists.
Cell Biology Studies
This hydrate form is relevant in cell biology research, particularly in studies concerning enzymatic functions and metabolic processes within cellular systems. It aids in elucidating the biochemical roles of Vitamin B6 derivatives.
| Molecular weight | 247.14 (anhydrous basis) |
|---|---|
| Empirical formula | C8H10NO6P · xH2O |
| Assay | ≥98% |
| Storage temperature | −20°C |
| Application | Enzyme inhibitor. |
| Melting point | 140-143 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Pyridoxal 5′-phosphate hydrate used for?
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Pyridoxal 5′-phosphate hydrate is primarily used as an enzyme inhibitor in biochemical research and for studies in cell biology and chemical synthesis. It is a derivative of Vitamin B6, playing a role in metabolic pathways.
What is the CAS number and formula for Pyridoxal 5′-phosphate hydrate?
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The CAS number for Pyridoxal 5′-phosphate hydrate is 853645-22-4, and its empirical formula is C8H10NO6P · xH2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Pyridoxal 5′-phosphate hydrate with an assay of ≥98%. This product is supplied for research and laboratory use. Tech Serve Solutions does not represent this product as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated.
How should Pyridoxal 5′-phosphate hydrate be handled and stored?
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Pyridoxal 5′-phosphate hydrate should be stored at −20°C. When handling, it is recommended to wear eyeshields and gloves, and use a type N95 (US) or type P1 (EN143) respirator filter. The compound has a WGK Germany rating of 3, indicating it is hazardous to water.
Is Pyridoxal 5′-phosphate hydrate a controlled substance?
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The provided data does not indicate that Pyridoxal 5′-phosphate hydrate is a controlled substance.
How is Pyridoxal 5′-phosphate hydrate packed, shipped, and exported?
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Tech Serve Solutions specialises in the global supply and export of fine chemicals, pharmaceutical intermediates, and laboratory reagents, including Pyridoxal 5′-phosphate hydrate. Specific packaging and shipping details are available upon request.
How can I request a sample or quote for Pyridoxal 5′-phosphate hydrate?
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To request a sample or a quote for Pyridoxal 5′-phosphate hydrate, please contact the Tech Serve Solutions sales team through our official channels. We are available to assist with your specific chemical needs.
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