Pyridinium tribromide
Pyridinium tribromide (CAS 39416-48-3), with the formula C5H5N·HBr·Br2 and a molecular weight of 319.82 g/mol, is a stable and easily handled source of electrophilic bromine. It serves as a versatile brominating agent in organic synthesis, facilitating the introduction of bromine atoms into various organic molecules. This reagent is particularly useful for alpha-bromination of carbonyl compounds and bromination of alkenes and aromatic systems.
- IUPAC
- Pyridine hydrobromide perbromide,Pyridine perbromide hydrobromide,Pyridinium bromide perbromide
- Synonyms
- Pyridine hydrobromide perbromidePyridine perbromide hydrobromidePyridinium bromide perbromide
Alpha-Bromination of Carbonyl Compounds
Pyridinium tribromide is employed for the selective bromination at the alpha-position of ketones and esters. This reaction is a key step in the synthesis of various intermediates used in pharmaceuticals and fine chemicals.
Bromination of Alkenes and Alkynes
The reagent effectively adds bromine across double and triple bonds, forming vicinal dibromides or related brominated adducts. These products are valuable building blocks in synthetic chemistry.
Bromination of Aromatic Compounds
It can be used for the electrophilic aromatic substitution to introduce bromine onto activated aromatic rings. This is a fundamental transformation for modifying aromatic structures in medicinal chemistry.
Oxidation Reactions
In certain contexts, pyridinium tribromide can act as a mild oxidizing agent, although its primary role is as a brominating agent.
| Molecular weight | 319.82 |
|---|---|
| Empirical formula | C5H5N·HBr·Br2 |
| Assay | 90% |
| Grade | technical |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Pyridinium tribromide primarily used for?
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Pyridinium tribromide is primarily used as a brominating agent in organic synthesis, particularly for alpha-bromination of carbonyl compounds and the bromination of alkenes and aromatic systems.
What is the CAS number and formula for Pyridinium tribromide?
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The CAS number for Pyridinium tribromide is 39416-48-3, and its formula is C5H5N·HBr·Br2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Pyridinium tribromide in a technical grade with an assay of 90%. We do not represent this product as USP, BP, or EP grade.
How should Pyridinium tribromide be handled safely?
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Pyridinium tribromide is corrosive and causes severe skin burns and eye damage (H314). Handle with appropriate personal protective equipment, including eyeshields, face shields, gloves, and a respirator, in a well-ventilated area. Refer to the safety data sheet for comprehensive handling instructions.
How is Pyridinium tribromide packed and shipped?
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Pyridinium tribromide is shipped as a UN 3261, Class 8, Packing Group II material, meeting stringent international regulations for hazardous chemical transport. TSS ensures compliance for global export.
How can I request a sample or quote for Pyridinium tribromide?
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To request a sample or quote, please contact our sales team via the website or by phone, providing your specific requirements and delivery details.
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