o-Xylylenediamine dihydrochloride
o-Xylylenediamine dihydrochloride (CAS: 21294-14-4), with the molecular formula C8H12N2 · 2HCl and a molecular weight of 209.12, is a chemical compound primarily utilised as an organic building block. It plays a role in chemical synthesis, particularly within nitrogen compound and polyamine research. This dihydrochloride salt form offers stability and ease of handling compared to the free base, making it suitable for various laboratory applications.
- IUPAC
- α,α′-Diamino-o-xylene dihydrochloride,1,2-Bis(aminomethyl)benzene dihydrochloride,ortho-Phenylene-bis(methylamine) dihydrochloride
- Synonyms
- α,α′-Diamino-o-xylene dihydrochloride1,2-Bis(aminomethyl)benzene dihydrochlorideortho-Phenylene-bis(methylamine) dihydrochloride

Organic Synthesis Intermediate
o-Xylylenediamine dihydrochloride serves as a valuable intermediate in the synthesis of more complex organic molecules. Its diamine structure allows for diverse reactions, enabling the construction of various heterocyclic compounds and polymers.
Building Block for Nitrogen Compounds
As a key building block, this compound is integral in the creation of novel nitrogen-containing compounds. It is frequently employed in research and development settings for exploring new chemical entities and materials.
Research and Development
Utilised in laboratory research, o-Xylylenediamine dihydrochloride is instrumental in academic and industrial R&D for developing new synthetic methodologies and exploring material science applications.
| Molecular weight | 209.12 |
|---|---|
| Empirical formula | C8H12N2 · 2HCl |
| Assay | ≥98%98.0-102.0% (AT) |
| Storage temperature | 2-8°C |
| Impurities tested | ~4% water |

Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is o-Xylylenediamine dihydrochloride used for?
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o-Xylylenediamine dihydrochloride is primarily used as an organic building block in chemical synthesis, particularly for creating nitrogen compounds and polyamines in research and development settings.
What is the CAS number and formula for o-Xylylenediamine dihydrochloride?
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The CAS number is 21294-14-4 and the empirical formula is C8H12N2 · 2HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies o-Xylylenediamine dihydrochloride with an assay of ≥98%. TSS does not represent this product as USP, BP, EP or any pharmacopoeia grade.
How should o-Xylylenediamine dihydrochloride be handled?
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Handle o-Xylylenediamine dihydrochloride with appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves. It is classified as harmful if swallowed, causes skin irritation, causes serious eye irritation, and may cause respiratory irritation (H302-H315-H319-H335).
How is this chemical exported and shipped?
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This chemical is exported and shipped according to international regulations for hazardous materials. Please contact TSS for specific shipping and export inquiries.
How can I request a sample or quote for o-Xylylenediamine dihydrochloride?
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To request a sample or a quote, please use the contact form on our website or reach out to our sales department directly.
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