1-(2-Tetrahydropyranyl)-1H-pyrazole-5-carboxaldehyde
1-(2-Tetrahydropyranyl)-1H-pyrazole-5-carboxaldehyde (CAS 957483-88-4; C9H12N2O2; molar mass 180.20 g/mol) is a heterocyclic building block in which a pyrazole-5-carbaldehyde carries a tetrahydropyran-2-yl (THP) group on the ring nitrogen. The aldehyde provides a reactive handle for condensation and coupling, while the THP group masks the pyrazole N-H. Tech Serve Solutions supplies this aldehyde to research, fine-chemical and pharmaceutical-intermediate users worldwide.
- Synonyms
- 1-(2-Tetrahydropyranyl)-1H-pyrazole-5-carboxaldehyde1-(Tetrahydro-2H-pyran-2-yl)-1H-pyrazole-5-carbaldehyde1-(Oxan-2-yl)-1H-pyrazole-5-carbaldehyde1-(2-Tetrahydropyranyl)pyrazole-5-carbaldehydeCAS 957483-88-4
Pyrazole building block for synthesis
Serves as an N-protected pyrazole-5-carbaldehyde scaffold for assembling more elaborate heterocyclic structures. It is widely used in medicinal- and discovery-chemistry programmes that build around the pyrazole motif.
Aldehyde for carbon-carbon and carbon-nitrogen bond formation
The formyl group undergoes reductive amination, Wittig and Knoevenagel-type condensations, and related additions. This makes the molecule a convenient handle for chain extension and side-chain elaboration.
N-protected intermediate
The tetrahydropyran-2-yl group masks the pyrazole N-H during multi-step sequences and can be removed under mild acidic conditions. This allows selective transformations elsewhere in the molecule before deprotection.
Reagent for pharmaceutical-intermediate routes
Used as a research-grade intermediate in the preparation of candidate pyrazole-based compounds. Tech Serve Solutions supplies it for laboratory and process-development use, not as a finished active ingredient.
| Molecular weight | 180.20 |
|---|---|
| Empirical formula | C9H12N2O2 |
| Density | 1.126 g/mL at 25 °C |
| Refractive index | n20/D 1.531 |
Hazard statements
- H302Harmful if swallowed
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-(2-Tetrahydropyranyl)-1H-pyrazole-5-carboxaldehyde used for?
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It is used as a heterocyclic building block in organic and medicinal chemistry. The aldehyde group enables condensations, reductive aminations and related couplings, while the tetrahydropyranyl group protects the pyrazole nitrogen during multi-step synthesis. It is supplied for research and pharmaceutical-intermediate development.
What is the CAS number and molecular formula of 1-(2-Tetrahydropyranyl)-1H-pyrazole-5-carboxaldehyde?
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The CAS number is 957483-88-4 and the molecular formula is C9H12N2O2, with a molecular weight of 180.20 g/mol. Reported physical data include a density of 1.126 g/mL at 25 C and a refractive index of n20/D 1.531.
What grade and purity does Tech Serve Solutions supply?
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It is supplied as a technical/research-grade building block for laboratory and process use. A specific assay value is confirmed on the certificate of analysis for each batch; we do not represent this material as USP, BP or EP pharmacopoeial grade. Please state your required specification when enquiring.
What are the safety and handling requirements?
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The material is classified GHS07 with the signal word Warning and hazard statement H302 (harmful if swallowed). Avoid ingestion, wear gloves and eye protection, handle with adequate ventilation, and consult the Safety Data Sheet before use. It is assigned German water-hazard class WGK 3, so prevent release to drains and watercourses.
How is 1-(2-Tetrahydropyranyl)-1H-pyrazole-5-carboxaldehyde packed, shipped and exported?
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It is packed in tightly sealed containers sized to the order, with full labelling and a Safety Data Sheet and certificate of analysis. As a specialist global supplier and exporter, Tech Serve Solutions arranges compliant export documentation and shipping to laboratory and industrial customers worldwide.
How do I request a sample or quote?
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Contact Tech Serve Solutions with your required quantity, target specification and delivery destination, and our team will confirm availability, packing options, lead time and documentation. Samples can be discussed for qualification, subject to availability.
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