1-(2-Thienyl)-1-propanone
1-(2-Thienyl)-1-propanone (CAS 13679-75-9), also known as 2-propionylthiophene, is an aryl ketone heterocyclic building block with the molecular formula C7H8OS and a molar mass of 140.20 g/mol. It is a thiophene bearing a propanoyl group, supplied as a liquid of 98% assay for use in fine-chemical and pharmaceutical-intermediate synthesis. Tech Serve Solutions supplies and exports it as a research and manufacturing-grade reagent to laboratories and industry worldwide.
- IUPAC
- 2-Propionylthiophene
- Synonyms
- 1-(2-Thienyl)-1-propanone2-Propionylthiophene1-(Thiophen-2-yl)propan-1-onePropionyl-2-thiopheneEthyl 2-thienyl ketoneCAS 13679-75-9
Heterocyclic building block
Serves as a thiophene-based building block in multistep organic synthesis. The reactive propanoyl (ethyl ketone) group offers a convenient handle for carbon-carbon and carbon-heteroatom bond formation.
Pharmaceutical intermediate synthesis
Used as an intermediate in the preparation of more complex thiophene-containing molecules of interest to medicinal and process chemistry. Specific routes depend on the customer's downstream chemistry.
Ketone-based transformations
The aryl ketone functionality undergoes typical reactions such as reduction to the corresponding alcohol, condensation, reductive amination and enolate chemistry, enabling access to substituted thiophene derivatives.
Laboratory reagent and reference material
Employed in research and development laboratories as a defined reagent for method development and small-scale synthesis where a characterised thiophene ketone is required.
| Molecular weight | 140.20 |
|---|---|
| Empirical formula | C7H8OS |
| Assay | 98% |
| Boiling point | 107 °C/11 mmHg(lit.) |
| Density | 1.126 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.553(lit.) |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H332Harmful if inhaled
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 101 °C / 213.8 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22 |
| Safety statements (S) | 36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-(2-Thienyl)-1-propanone used for?
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It is used mainly as a heterocyclic building block and synthetic intermediate. The thiophene ring and reactive propanoyl group make it useful for preparing more complex thiophene derivatives in fine-chemical and pharmaceutical-intermediate synthesis.
What is the CAS number and molecular formula of 1-(2-Thienyl)-1-propanone?
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The CAS number is 13679-75-9 and the molecular formula is C7H8OS, with a molecular weight of 140.20 g/mol. It is also known as 2-propionylthiophene (MDL MFCD00005446, EC 237-182-8).
What grade and purity does Tech Serve Solutions supply?
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It is supplied as a research and manufacturing-grade reagent with a typical assay of 98%. We do not represent it as USP, BP or EP pharmacopoeial grade. A certificate of analysis is provided with each batch, and specifications can be confirmed at the time of enquiry.
What are the safety and handling requirements for 1-(2-Thienyl)-1-propanone?
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It is classified under GHS07 with the signal word Warning and hazard statements H302 (harmful if swallowed), H312 (harmful in contact with skin) and H332 (harmful if inhaled). Wear protective gloves, eye and face protection (P280), avoid skin and eye contact and inhalation, and consult the Safety Data Sheet before use. It is assigned WGK 3 (highly hazardous to water in Germany).
How is 1-(2-Thienyl)-1-propanone packed, shipped and exported?
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It is packed as a liquid in suitable laboratory and bulk containers with full labelling and a Safety Data Sheet. Tech Serve Solutions exports worldwide with appropriate documentation; packaging and transport are arranged to meet applicable dangerous-goods and destination-country requirements.
How do I request a sample or quote?
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Contact Tech Serve Solutions with your required quantity, purity and delivery destination. We will confirm availability, specifications and lead time, and can provide a sample or formal quotation for laboratory or commercial volumes.
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