O-Acetylmandelic chloride
O-Acetylmandelic chloride (CAS: 1638-63-7) is an organic compound with the linear formula CH3CO2CH(C6H5)COCl and a molecular weight of 212.63 g/mol. It functions as a versatile chemical intermediate and building block in organic synthesis. This acid halide is primarily utilised in research and development laboratories for the construction of more complex organic molecules, contributing to advancements in chemical research and pharmaceutical development.
- IUPAC
- 2-Acetoxy-2-phenylacetyl chloride
- Synonyms
- 2-Acetoxy-2-phenylacetyl chloride
Organic Synthesis Intermediate
O-Acetylmandelic chloride serves as a reactive intermediate in the synthesis of various organic compounds. Its acid chloride functionality readily participates in acylation reactions, making it valuable for introducing the 2-acetoxy-2-phenylacetyl group into target molecules.
Building Block for Complex Molecules
This compound acts as a crucial building block in multi-step synthetic pathways. Its structure allows for the elaboration into diverse molecular architectures, finding application in the development of novel chemical entities for research purposes.
Pharmaceutical Research
In pharmaceutical research, O-Acetylmandelic chloride can be employed in the synthesis of potential drug candidates or their precursors. Its incorporation into molecular structures may contribute to the development of new therapeutic agents.
| Molecular weight | 212.63 |
|---|---|
| Linear formula | CH3CO2CH(C6H5)COCl |
| Assay | ≥95% |
| Boiling point | 125-130 °C/10 mmHg(lit.) |
| Density | 0.943 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.514(lit.) |
Hazard statements
- H314Causes severe skin burns and eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34-36/37 |
| Safety statements (S) | 26-27-28-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is O-Acetylmandelic chloride primarily used for?
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O-Acetylmandelic chloride is primarily used as a reactive intermediate and building block in organic synthesis for research and development purposes, including potential applications in pharmaceutical research.
What are the CAS number and chemical formula for O-Acetylmandelic chloride?
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The CAS number for O-Acetylmandelic chloride is 1638-63-7, and its linear chemical formula is CH3CO2CH(C6H5)COCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies O-Acetylmandelic chloride with an assay of ">=95%". This product is intended for research and technical use, and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should O-Acetylmandelic chloride be handled safely?
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O-Acetylmandelic chloride is classified as corrosive and may cause respiratory irritation (H314, H335). Handle with appropriate personal protective equipment including full-face respirators, chemical-resistant gloves, goggles, and faceshields in a well-ventilated area. Refer to the Safety Data Sheet for detailed handling procedures.
Is O-Acetylmandelic chloride a controlled substance?
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The provided data does not indicate that O-Acetylmandelic chloride is a controlled substance.
How is O-Acetylmandelic chloride packed and shipped?
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O-Acetylmandelic chloride is shipped as UN 3265, Class 8, Packing Group II, indicating it is a corrosive material requiring specialised packaging and transportation procedures.
How can I request a sample or quote for O-Acetylmandelic chloride?
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To request a sample or quote for O-Acetylmandelic chloride, please contact the Tech Serve Solutions sales team through our website or designated contact channels.
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