O-(tert-Butyldimethylsilyl)-N-tosylhydroxylamine
O-(tert-Butyldimethylsilyl)-N-tosylhydroxylamine (CAS: 1028432-04-3, C13H23NO3SSi) is a synthetic organic reagent with a molecular weight of 301.48 g/mol. It is characterised by its ability to participate in non-halogen C-X bond formation reactions, often employed in sophisticated chemical synthesis. This compound is a valuable tool in organic chemistry, particularly for researchers requiring precise control over bond construction in complex molecule synthesis, including applications related to the Mitsunobu reaction.
- IUPAC
- O-(tert-Butyldimethylsilyl)-N-(toluenesulfonyl)hydroxylamine,O-TBS-N-tosylhydroxylamine,TsNHOTBDMS,TsNHOTBS
- Synonyms
- O-(tert-Butyldimethylsilyl)-N-(toluenesulfonyl)hydroxylamineO-TBS-N-tosylhydroxylamineTsNHOTBDMSTsNHOTBS
C-X Bond Formation
This reagent is specifically employed for non-halogen C-X bond formations, allowing for the controlled synthesis of new carbon-heteroatom bonds. Its structure facilitates specific reaction pathways crucial in advanced organic synthesis.
Chemical Synthesis
O-(tert-Butyldimethylsilyl)-N-tosylhydroxylamine serves as a key building block or reagent in multi-step chemical synthesis. It enables chemists to introduce specific functional groups or structural motifs into target molecules.
Mitsunobu Reaction
The compound finds application in variations or related methodologies of the Mitsunobu reaction. This allows for stereoselective inversions or functional group transformations under mild conditions.
Synthetic Reagents
As a specialised synthetic reagent, it is used in research and development laboratories for the creation of novel compounds and the optimisation of synthetic routes. Its unique reactivity profile is valuable for challenging transformations.
| Molecular weight | 301.48 |
|---|---|
| Empirical formula | C13H23NO3SSi |
| Assay | 97% |
| Melting point | 90-96 °C |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3259PSN1 8 / PGII |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is O-(tert-Butyldimethylsilyl)-N-tosylhydroxylamine used for?
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O-(tert-Butyldimethylsilyl)-N-tosylhydroxylamine is primarily used in chemical synthesis for non-halogen C-X bond formation and is particularly relevant in applications involving the Mitsunobu reaction.
What are the CAS number and formula for O-(tert-Butyldimethylsilyl)-N-tosylhydroxylamine?
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The CAS number for O-(tert-Butyldimethylsilyl)-N-tosylhydroxylamine is 1028432-04-3, and its empirical formula is C13H23NO3SSi.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies O-(tert-Butyldimethylsilyl)-N-tosylhydroxylamine with a minimum purity of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should O-(tert-Butyldimethylsilyl)-N-tosylhydroxylamine be handled?
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This compound is classified as Danger with hazard statement H314 (Causes severe skin burns and eye damage). Appropriate personal protective equipment including eyeshields, face shields, gloves, and suitable respiratory protection (e.g., N100 respirator) must be used. Handle in a well-ventilated area and avoid contact with skin, eyes, and clothing.
Is O-(tert-Butyldimethylsilyl)-N-tosylhydroxylamine a controlled substance?
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The provided data does not indicate that O-(tert-Butyldimethylsilyl)-N-tosylhydroxylamine is a controlled substance.
How is this chemical packed and shipped?
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O-(tert-Butyldimethylsilyl)-N-tosylhydroxylamine is shipped as UN 3259, Class 8, Packing Group II. It is exported by Tech Serve Solutions following all relevant transport regulations.
How can I request a sample or quote for this product?
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To request a sample or a quote for O-(tert-Butyldimethylsilyl)-N-tosylhydroxylamine, please contact our sales team through the website or by phone.
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