O-(2-Aminoethyl)-O′-(2-carboxyethyl)polyethylene glycol 5,000 hydrochloride
O-(2-Aminoethyl)-O′-(2-carboxyethyl)polyethylene glycol 5,000 hydrochloride (CAS: 187848-66-4) is a heterobifunctional polyethylene glycol derivative with a molar mass of approximately 5,000 g/mol. This amine-terminated and carboxyl-terminated PEG linker offers versatile conjugation possibilities. It is primarily utilised in chemical synthesis, materials science, and chemical biology applications, including drug delivery systems and the development of novel biomaterials.
- Synonyms
- NH2-PEG-COOH·HClHCl·HOOC-PEG-NH2
Biomaterial Development
This PEG derivative can be employed in the creation of vesicle polymersomes and for immobilising functionalised enzymes, as demonstrated in the aggregation of functionalised peroxidase of permethylated ß-cyclodextrin-appended polystyrene giant amphiphiles.
Drug Delivery Systems
It serves as a platform for oligonucleotide delivery via a PEG prodrug approach. Additionally, it is used in folate-receptor-targeted delivery systems for nano-aggregates, stabilised by doxorubicin-PEG-folate conjugates.
Chemical Synthesis and Modification
The amine and carboxyl functionalities allow for diverse chemical conjugations, making it a valuable tool in synthetic chemistry for modifying molecules or surfaces.
| Application | Used for:• Aggregation to vesicle polymersomes and immobilization of functionalized peroxidase of permethylated ß-cyclodextrin-appended polystyrene giant amphiphile1• Platform for oligonucleotide delivery utilizing PEG prodrug approach2• Folate-receptor-targeted delivery of doxorubicin nano-aggregates stabilized by doxorubicin-PEG-folate conjugate3 |
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| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
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| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Mol Wt | Mp 5,000 |
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Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is O-(2-Aminoethyl)-O′-(2-carboxyethyl)polyethylene glycol 5,000 hydrochloride used for?
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This compound is used in chemical synthesis, materials science, and chemical biology, including applications in drug delivery systems, creating biomaterials like vesicle polymersomes, and for immobilising functionalised enzymes.
What is the CAS number and formula for this compound?
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The CAS number is 187848-66-4. The exact chemical formula is not provided in the product data.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies O-(2-Aminoethyl)-O′-(2-carboxyethyl)polyethylene glycol 5,000 hydrochloride with a molar mass of approximately 5,000 g/mol. TSS does not represent this product as USP/BP/EP grade.
How should this chemical be handled safely?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The compound is classified with a WGK of 3 in Germany, indicating it is hazardous to water.
How is this chemical packed, shipped, and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. Specific packing and shipping details are available upon request.
How can I request a sample or quote?
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To request a sample or quote for O-(2-Aminoethyl)-O′-(2-carboxyethyl)polyethylene glycol 5,000 hydrochloride, please contact the Tech Serve Solutions sales team.
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