O-(2-Aminoethyl)-O′-(2-azidoethyl)heptaethylene glycol
O-(2-Aminoethyl)-O′-(2-azidoethyl)heptaethylene glycol (CAS: 857891-82-8) is a heterobifunctional polyethylene glycol derivative with amine and azide end groups. This compound, with the molecular formula C18H38N4O8 and a molecular weight of 438.52 g/mol, serves as a versatile building block in chemical synthesis and materials science. Its unique structure allows for orthogonal conjugation strategies, making it valuable in bioconjugation, surface modification, and the development of advanced materials.
- IUPAC
- Azido-PEG-amine (n=8)

Bioconjugation Chemistry
This amine-PEG-azide linker is employed to covalently attach biomolecules or other functional moieties, leveraging the click chemistry potential of the azide group and the amine for further modifications or interactions.
Materials Science
Used in surface functionalization and the synthesis of novel polymeric materials. The PEG backbone imparts desirable properties such as biocompatibility and water solubility to the modified surfaces or resulting polymers.
Drug Delivery Systems
Can be utilized in the design of targeted drug delivery vehicles. The bifunctional nature allows for incorporation into nanoparticle structures or conjugation to therapeutic agents.
Chemical Synthesis
Serves as a crucial building block in multi-step organic synthesis, enabling the introduction of polyethylene glycol chains with distinct terminal functionalities.
| Molecular weight | 438.52 |
|---|---|
| Empirical formula | C18H38N4O8 |
| Assay | ≥90% (oligomer purity) |
| Storage temperature | 2-8°C |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is O-(2-Aminoethyl)-O′-(2-azidoethyl)heptaethylene glycol used for?
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This compound is primarily used as a building block in chemical synthesis, particularly for bioconjugation and materials science applications, owing to its amine and azide functionalities.
What is the CAS number and molecular formula for O-(2-Aminoethyl)-O′-(2-azidoethyl)heptaethylene glycol?
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The CAS number is 857891-82-8, and the molecular formula is C18H38N4O8.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies O-(2-Aminoethyl)-O′-(2-azidoethyl)heptaethylene glycol with an assay of ≥90% oligomer purity. This product is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should O-(2-Aminoethyl)-O′-(2-azidoethyl)heptaethylene glycol be handled and stored?
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This compound requires careful handling due to its H315, H319, and H335 hazard statements (causes skin irritation, serious eye irritation, and may cause respiratory irritation). It should be stored at 2-8°C. Appropriate personal protective equipment, including eyeshields and gloves, should be worn. Refer to the Safety Data Sheet for detailed handling instructions.
Is this chemical a controlled substance?
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The provided data does not indicate that O-(2-Aminoethyl)-O′-(2-azidoethyl)heptaethylene glycol is a controlled substance.
How is this chemical packed, shipped, and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals and laboratory reagents. Specific packing and shipping details are provided upon request and comply with international regulations.
How can I request a quote or sample?
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To request a quote or sample of O-(2-Aminoethyl)-O′-(2-azidoethyl)heptaethylene glycol, please contact our sales team via the website or direct inquiry.
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