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Tetrahydrothiophene

CAS 110-01-0C4H8SChemical Synthesis

Tetrahydrothiophene (CAS: 110-01-0; Formula: C4H8S; MW: 88.17) is a cyclic organic compound featuring a sulfur atom within a five-membered ring. This clear liquid is primarily utilised as a building block in chemical synthesis, particularly for the creation of heterocyclic compounds. Its properties make it a valuable reagent in various organic transformations where a thiolane moiety is required.

IUPAC
Tetramethylene sulfide,Thiolane,Thiophane
Synonyms
Tetramethylene sulfideThiolaneThiophane
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Tetrahydrothiophene (C4H8S) — chemical structure, CAS 110-01-0; Chemistry, fine chemical supplied by Tech Serve Solutions
Building BlocksC4 to C6Chemical SynthesisHeterocyclic Building BlocksThiophenes
01 /Applications

Chemical Synthesis Intermediate

Tetrahydrothiophene serves as a key intermediate in the synthesis of more complex organic molecules. It is frequently employed in reactions requiring the introduction of a thiolane ring system.

Heterocyclic Chemistry

As a fundamental heterocyclic building block, it finds application in the development of novel thiophene derivatives and related sulfur-containing compounds for research and industrial purposes.

Research Reagent

Available in high purity, Tetrahydrothiophene is used in academic and industrial research laboratories for various organic chemistry studies and method development.

02 /Properties
Molecular weight88.17
Empirical formulaC4H8S
Assay99%
Boiling point119 °C(lit.)
Density1 g/mL at 25 °C(lit.)
Refractive indexn20/D 1.504(lit.)
Vapour pressure18 mmHg (25 °C)
Melting point−96 °C(lit.)
03 /Safety & handling
GHS hazard pictogram: Flammable (GHS02)
Flammable
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Danger

Hazard statements

  • H225Highly flammable liquid and vapour
  • H302Harmful if swallowed
  • H312Harmful in contact with skin
  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H332Harmful if inhaled
  • H412Harmful to aquatic life with long-lasting effects

Precautionary statements

  • P210Keep away from heat, sparks and open flames. No smoking
  • P273Avoid release to the environment
  • P280Wear protective gloves, clothing and eye/face protection
  • P305IF IN EYES
Protective equipmentEyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Flash point13 °C / 55.4 °F
Transport (UN / ADR)UN 2412 3 / PGII
Water hazard class (WGK, DE)2
Hazard codes (EU)F,Xn
Risk statements (R)11-20/21/22-36/38-52/53
Safety statements (S)16-23-36/37-61

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
110-01-0
MDL number
MFCD00005476
PubChem substance
24899981
Beilstein registry
102392
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Tetrahydrothiophene used for?

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Tetrahydrothiophene is used as a building block in chemical synthesis, particularly for creating heterocyclic compounds, and as a research reagent.

What is the CAS number and formula for Tetrahydrothiophene?

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The CAS number for Tetrahydrothiophene is 110-01-0, and its chemical formula is C4H8S.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies Tetrahydrothiophene with an assay of 99%. We do not represent this product as USP, BP, or EP grade.

How should Tetrahydrothiophene be handled safely?

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Tetrahydrothiophene is a flammable liquid and vapour (H225), harmful if swallowed, inhaled, or in contact with skin (H302, H332, H312), and causes skin and eye irritation (H315, H319). It is also harmful to aquatic life with long lasting effects (H412). Handle in a well-ventilated area, away from ignition sources, using appropriate personal protective equipment including gloves, safety goggles, and a suitable respirator.

How is Tetrahydrothiophene packed, shipped, and exported?

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Tetrahydrothiophene is typically packed in accordance with UN 2412, Class 3, Packing Group II regulations for safe transport. TSS exports globally, adhering to all international shipping and customs requirements.

How can I request a sample or quote for Tetrahydrothiophene?

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To request a sample or a quotation for Tetrahydrothiophene, please contact the Tech Serve Solutions sales team via our website or direct email, specifying your quantity requirements.

Need Tetrahydrothiophene in a specific grade or volume?