O-(2-Aminoethyl)-O′-(2-azidoethyl)pentaethylene glycol
O-(2-Aminoethyl)-O′-(2-azidoethyl)pentaethylene glycol (CAS 957486-82-7) is a heterobifunctional polyethylene glycol derivative with the empirical formula C14H30N4O6 and a molecular weight of 350.41 g/mol. This amine-PEG-azide linker is valuable in bioconjugation and chemical synthesis due to its distinct terminal functional groups. It facilitates the precise attachment of molecules and is widely employed in materials science and chemical biology research.
- IUPAC
- Azido-PEG-amine (n=6)
Bioconjugation
This compound serves as a versatile linker for conjugating biomolecules, enabling the precise attachment of proteins, peptides, or nucleic acids. The terminal amine and azide groups allow for orthogonal conjugation strategies.
Surface Functionalization
It can be used to modify surfaces, introducing amine and azide functionalities for subsequent attachment of various molecules or nanoparticles. This is crucial for developing advanced materials and biosensors.
Drug Delivery Systems
The PEG backbone offers favourable pharmacokinetic properties, making this linker suitable for developing targeted drug delivery systems. It can be incorporated into conjugates designed for improved solubility and reduced immunogenicity.
Chemical Synthesis
As a building block, it enables the synthesis of complex molecular architectures. The distinct reactivity of the amine and azide groups allows for sequential and selective reactions in multi-step synthetic pathways.
| Molecular weight | 350.41 |
|---|---|
| Empirical formula | C14H30N4O6 |
| Assay | ≥90% (oligomer purity) |
| Storage temperature | 2-8°C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is O-(2-Aminoethyl)-O′-(2-azidoethyl)pentaethylene glycol used for?
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This compound is primarily used in bioconjugation, surface functionalization, drug delivery systems, and chemical synthesis as a versatile linker with amine and azide terminal groups.
What are the CAS number and molecular formula?
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The CAS number is 957486-82-7 and the molecular formula is C14H30N4O6.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies O-(2-Aminoethyl)-O′-(2-azidoethyl)pentaethylene glycol with an oligomer purity of ≥90%. We do not represent this product as USP, BP, or EP grade.
What are the safety and handling considerations?
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This product is classified as a Warning (GHS07) and may cause skin irritation (H315), eye irritation (H319), and respiratory irritation (H335). Appropriate personal protective equipment, including eyeshields and gloves, is recommended. Consult the Safety Data Sheet for detailed handling instructions.
How is this chemical packed and exported?
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This chemical is typically stored at 2-8°C and is available for global export by Tech Serve Solutions, a trusted supplier with extensive experience in handling and shipping fine chemicals.
How can I request a quote or sample?
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To request a quote or sample of O-(2-Aminoethyl)-O′-(2-azidoethyl)pentaethylene glycol, please contact our sales team through the Tech Serve Solutions website.
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