O-(2-Aminoethyl)-O′-(2-azidoethyl)nonaethylene glycol
O-(2-Aminoethyl)-O′-(2-azidoethyl)nonaethylene glycol (CAS: 912849-73-1) is a heterobifunctional polyethylene glycol (PEG) derivative with the chemical formula C22H46N4O10 and a molecular weight of 526.62 g/mol. This compound features both an amine (NH2) and an azide (N3) functional group, linked by a nonaethylene glycol chain. It is a versatile building block used in chemical biology, conjugation chemistry, and materials science for linking molecules or surfaces.
- IUPAC
- Azido-PEG-amine (n=10)

Bioconjugation
Utilised for conjugating biomolecules such as proteins, peptides, or nucleic acids. The amine terminus can react with activated esters or aldehydes, while the azide terminus is available for click chemistry reactions with alkynes.
Materials Science
Applied in surface modification to introduce specific functionalities. The PEG linker provides hydrophilicity and can improve biocompatibility, while the terminal groups enable covalent attachment to various substrates.
Drug Delivery Systems
Incorporated into the design of nanoparticles or drug carriers to enhance solubility, circulation time, or targeted delivery through functionalisation.
Chemical Synthesis
Serves as a versatile intermediate for the synthesis of more complex molecules and polymers, leveraging the orthogonal reactivity of the amine and azide groups.
| Molecular weight | 526.62 |
|---|---|
| Empirical formula | C22H46N4O10 |
| Assay | ≥90% (oligomer purity) |
| Storage temperature | 2-8°C |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is O-(2-Aminoethyl)-O′-(2-azidoethyl)nonaethylene glycol used for?
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This compound is a heterobifunctional PEG linker primarily used in bioconjugation, materials science, drug delivery systems, and chemical synthesis to connect molecules or modify surfaces.
What are the CAS number and chemical formula?
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The CAS number is 912849-73-1 and the chemical formula is C22H46N4O10.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies O-(2-Aminoethyl)-O′-(2-azidoethyl)nonaethylene glycol with an oligomer purity of ≥90%. This product is intended for research and technical use and is not represented as USP, BP, EP, or other pharmacopoeial grades.
How should this chemical be handled safely?
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This compound is a Warning hazard and is classified with H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Appropriate personal protective equipment, including eyeshields and gloves, must be worn. Ensure adequate ventilation or use a suitable respirator. Refer to the safety data sheet for full details.
How is this product packed and shipped?
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This chemical is typically stored at 2-8°C. For shipping and export inquiries, please contact Tech Serve Solutions directly for specific packaging and logistical arrangements.
How can I request a sample or quote?
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To request a sample or obtain a quotation for O-(2-Aminoethyl)-O′-(2-azidoethyl)nonaethylene glycol, please contact our sales team through the website or by phone.
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