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O-(2-Aminoethyl)-O′-(2-azidoethyl)nonaethylene glycol

CAS 912849-73-1C22H46N4O10Chemical Synthesis

O-(2-Aminoethyl)-O′-(2-azidoethyl)nonaethylene glycol (CAS: 912849-73-1) is a heterobifunctional polyethylene glycol (PEG) derivative with the chemical formula C22H46N4O10 and a molecular weight of 526.62 g/mol. This compound features both an amine (NH2) and an azide (N3) functional group, linked by a nonaethylene glycol chain. It is a versatile building block used in chemical biology, conjugation chemistry, and materials science for linking molecules or surfaces.

IUPAC
Azido-PEG-amine (n=10)
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O-(2-Aminoethyl)-O′-(2-azidoethyl)nonaethylene glycol (C22H46N4O10) — chemical structure, CAS 912849-73-1; Chemistry, fine chemical supplied by Tech Serve Solutions
Aliphatic AzidesAmine FunctionalizedAmine-PEG-Azide (NH2-PEG-N3)Azide (-N3) FunctionalizedAzide-PEG-Amine (N3-PEG-NH2)AzidesBuilding BlocksChemical BiologyChemical SynthesisAlkynes and Other Reagents
01 /Applications

Bioconjugation

Utilised for conjugating biomolecules such as proteins, peptides, or nucleic acids. The amine terminus can react with activated esters or aldehydes, while the azide terminus is available for click chemistry reactions with alkynes.

Materials Science

Applied in surface modification to introduce specific functionalities. The PEG linker provides hydrophilicity and can improve biocompatibility, while the terminal groups enable covalent attachment to various substrates.

Drug Delivery Systems

Incorporated into the design of nanoparticles or drug carriers to enhance solubility, circulation time, or targeted delivery through functionalisation.

Chemical Synthesis

Serves as a versatile intermediate for the synthesis of more complex molecules and polymers, leveraging the orthogonal reactivity of the amine and azide groups.

02 /Properties
Molecular weight526.62
Empirical formulaC22H46N4O10
Assay≥90% (oligomer purity)
Storage temperature2-8°C
03 /Safety & handling
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Warning

Hazard statements

  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H335May cause respiratory irritation

Precautionary statements

  • P261Avoid breathing dust, fume, gas or vapours
  • P305IF IN EYES
Protective equipmentEyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Water hazard class (WGK, DE)3
Hazard codes (EU)Xi
Risk statements (R)36/37/38
Safety statements (S)26

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
912849-73-1
MDL number
MFCD03453246
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is O-(2-Aminoethyl)-O′-(2-azidoethyl)nonaethylene glycol used for?

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This compound is a heterobifunctional PEG linker primarily used in bioconjugation, materials science, drug delivery systems, and chemical synthesis to connect molecules or modify surfaces.

What are the CAS number and chemical formula?

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The CAS number is 912849-73-1 and the chemical formula is C22H46N4O10.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies O-(2-Aminoethyl)-O′-(2-azidoethyl)nonaethylene glycol with an oligomer purity of ≥90%. This product is intended for research and technical use and is not represented as USP, BP, EP, or other pharmacopoeial grades.

How should this chemical be handled safely?

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This compound is a Warning hazard and is classified with H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Appropriate personal protective equipment, including eyeshields and gloves, must be worn. Ensure adequate ventilation or use a suitable respirator. Refer to the safety data sheet for full details.

How is this product packed and shipped?

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This chemical is typically stored at 2-8°C. For shipping and export inquiries, please contact Tech Serve Solutions directly for specific packaging and logistical arrangements.

How can I request a sample or quote?

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To request a sample or obtain a quotation for O-(2-Aminoethyl)-O′-(2-azidoethyl)nonaethylene glycol, please contact our sales team through the website or by phone.

Need O-(2-Aminoethyl)-O′-(2-azidoethyl)nonaethylene glycol in a specific grade or volume?