2-Amino-4-chloropyrimidine
2-Amino-4-chloropyrimidine (CAS: 3993-78-0) is a heterocyclic organic compound with the formula C4H4ClN3 and a molecular weight of 129.55 g/mol. This chemical serves as a valuable building block in organic synthesis, particularly in the preparation of more complex molecules. It has been utilised as a substrate in palladium-catalyzed cyanation reactions. Tech Serve Solutions supplies this compound with an assay of 97%.

Organic Synthesis
Utilised as a key intermediate and building block in the synthesis of various organic compounds. Its structure allows for diverse chemical modifications.
Palladium-Catalyzed Cyanation
Acts as a substrate in palladium-catalyzed cyanation reactions, a crucial transformation for introducing nitrile groups into organic molecules.
Heterocyclic Chemistry
A useful component in the field of heterocyclic chemistry for constructing more complex pyrimidine derivatives and related structures.
| Molecular weight | 129.55 |
|---|---|
| Empirical formula | C4H4ClN3 |
| Assay | 97% |
| Storage temperature | 2-8°C |
| Application | Substrate used in a palladium-catalyzed cyanation with zinc(II) cyanide.1 |
| Melting point | 155-160 °C (dec.) |


Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-37/38-41 |
| Safety statements (S) | 26-36/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Amino-4-chloropyrimidine used for?
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2-Amino-4-chloropyrimidine is primarily used as a building block in organic synthesis and as a substrate in palladium-catalyzed cyanation reactions.
What are the CAS number and formula for 2-Amino-4-chloropyrimidine?
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The CAS number for 2-Amino-4-chloropyrimidine is 3993-78-0, and its chemical formula is C4H4ClN3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Amino-4-chloropyrimidine with a minimum assay of 97%. This product is suitable for research and chemical synthesis purposes and is not represented as USP, BP, or EP grade.
How should 2-Amino-4-chloropyrimidine be handled safely?
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Handling requires caution due to its hazardous nature. It is harmful if swallowed (H302), causes skin irritation (H315), causes serious eye damage (H318), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, face shields, and gloves, must be worn. Ensure adequate ventilation.
How is 2-Amino-4-chloropyrimidine packed and shipped?
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Tech Serve Solutions exports and supplies 2-Amino-4-chloropyrimidine, ensuring appropriate packaging for safe transport according to regulations.
How can I request a quote or sample?
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To request a quote or sample of 2-Amino-4-chloropyrimidine, please contact our sales team via the website or by telephone.
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