2-Amino-4-fluorobenzoic acid
2-Amino-4-fluorobenzoic acid (CAS 446-32-2), with the molecular formula H2NC6H3(F)CO2H and a molecular weight of 155.13 g/mol, is a fluorinated derivative of anthranilic acid. It serves as a valuable building block in organic synthesis, particularly in the development of novel compounds within chemical biology and peptide chemistry. Its specific substitution pattern makes it a useful intermediate for introducing fluorinated aromatic moieties into more complex molecular structures.
- IUPAC
- 4-Fluoroanthranilic acid
- Synonyms
- 4-Fluoroanthranilic acid

Organic Synthesis Intermediate
This compound acts as a key intermediate in the synthesis of diverse organic molecules. Its structure allows for various chemical transformations, enabling the construction of complex molecular architectures.
Chemical Biology Research
Used as a research chemical, it contributes to the exploration of chemical biology, potentially aiding in the study of biological processes or the development of new biochemical tools.
Peptide and Medicinal Chemistry
As an unnatural amino acid derivative, it is employed in peptide chemistry and medicinal chemistry for the design and synthesis of modified peptides or drug candidates.
Fluorinated Compound Synthesis
Facilitates the introduction of a fluorine atom onto an aromatic ring, which is a common strategy in medicinal chemistry to modulate the properties of drug molecules.
| Molecular weight | 155.13 |
|---|---|
| Linear formula | H2NC6H3(F)CO2H |
| Assay | 97% |
| Melting point | 192-196 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Amino-4-fluorobenzoic acid used for?
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2-Amino-4-fluorobenzoic acid is primarily used as an intermediate in organic synthesis, particularly in areas such as chemical biology, peptide chemistry, and the development of fluorinated compounds.
What is the CAS number and formula for 2-Amino-4-fluorobenzoic acid?
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The CAS number is 446-32-2 and the linear formula is H2NC6H3(F)CO2H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Amino-4-fluorobenzoic acid with a minimum assay of 97%. This product is not supplied in USP, BP, EP, nutraceutical, or food grades.
How should 2-Amino-4-fluorobenzoic acid be handled safely?
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Handle with appropriate personal protective equipment including a dust mask type N95 (US), eyeshields, and gloves. Avoid breathing dust and ensure adequate ventilation. Refer to the safety data sheet for comprehensive handling information.
Does Tech Serve Solutions export 2-Amino-4-fluorobenzoic acid?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 2-Amino-4-fluorobenzoic acid.
How can I request a sample or quote for 2-Amino-4-fluorobenzoic acid?
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Please contact our sales department via our website or by phone to request a sample or a quotation for 2-Amino-4-fluorobenzoic acid.
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