2-Amino-4-fluorophenol
2-Amino-4-fluorophenol (CAS: 399-97-3), with the molecular formula C6H6FNO and a molecular weight of 127.12 g/mol, is a fluorinated organic building block. This compound serves as a valuable intermediate in chemical synthesis, particularly for the development of complex organic molecules. Its structure, featuring both an amine and a hydroxyl group on a fluorinated benzene ring, makes it a versatile reagent in various research and development applications within the pharmaceutical and agrochemical sectors.
- IUPAC
- 5-Fluoro-2-hydroxyaniline
- Synonyms
- 5-Fluoro-2-hydroxyaniline

Pharmaceutical Intermediate
2-Amino-4-fluorophenol is employed as a key building block in the synthesis of active pharmaceutical ingredients (APIs). Its specific fluorinated aryl structure is often incorporated into drug candidates to modulate pharmacokinetic and pharmacodynamic properties.
Agrochemical Synthesis
This compound finds application in the development of novel agrochemicals. The fluorine atom can enhance the biological activity and metabolic stability of pesticides and herbicides.
Organic Synthesis Reagent
As a versatile organic building block, 2-Amino-4-fluorophenol is utilised in a wide range of synthetic organic chemistry procedures for constructing specialised molecules.
Material Science
The unique properties conferred by the fluorine substituent make this compound a potential candidate for incorporation into advanced materials and polymers.
| Molecular weight | 127.12 |
|---|---|
| Empirical formula | C6H6FNO |
| Assay | 96% |
| Melting point | 130-135 °C |

Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Amino-4-fluorophenol used for?
+
2-Amino-4-fluorophenol is primarily used as a building block and intermediate in organic synthesis, particularly for pharmaceuticals and agrochemicals.
What is the CAS number and formula for 2-Amino-4-fluorophenol?
+
The CAS number is 399-97-3, and its molecular formula is C6H6FNO.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 2-Amino-4-fluorophenol with a minimum assay of 96%. We do not represent this product as USP, BP, or EP grade.
How should 2-Amino-4-fluorophenol be handled safely?
+
Handle 2-Amino-4-fluorophenol with appropriate personal protective equipment, including a dust mask (N95 recommended), eyeshields, and gloves. Ensure good ventilation and avoid inhalation, skin, and eye contact, as it is harmful if swallowed, causes skin irritation, eye irritation, and may cause respiratory irritation.
Is 2-Amino-4-fluorophenol exported by Tech Serve Solutions?
+
Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 2-Amino-4-fluorophenol.
How can I request a quote or sample for 2-Amino-4-fluorophenol?
+
To request a quote or sample, please contact our sales team through the website or by phone, providing your specific requirements and shipping details.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis