(11bR,11′bR)-4,4′-(9,9-Dimethyl-9H-xanthene-4,5-diyl)bis-dinaphtho[2,1-d:1′, 2′-f][1,3,2]dioxaphosphepin
(11bR,11′bR)-4,4′-(9,9-Dimethyl-9H-xanthene-4,5-diyl)bis-dinaphtho[2,1-d:1′, 2′-f][1,3,2]dioxaphosphepin (CAS: 349114-63-2) is a chiral diphosphonite ligand with the molecular formula C55H36O5P2. This compound is primarily utilised as a specialised reagent in asymmetric synthesis, particularly for enantioselective hydrogenation reactions. Its unique structure facilitates high stereocontrol, making it valuable in producing chiral molecules for pharmaceutical and fine chemical industries.
- IUPAC
- R, R-Reetz X-Diphosphonite
- Synonyms
- 9-Dimethyl-9H-xanthene-4,5-diyl)bis-dinaphtho[2,1-d:1′, 2′-f][1,3,2]dioxaphosphepin, 349114-63-2, C55H36O5P2, R, R-Reetz X-Diphosphonite
![(11bR,11′bR)-4,4′-(9,9-Dimethyl-9H-xanthene-4,5-diyl)bis-dinaphtho[2,1-d:1′, 2′-f][1,3,2]dioxaphosphepin (C55H36O5P2) — chemical structure, CAS 349114-63-2; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F349114-63-2.png&w=3840&q=75)
Asymmetric Transfer Hydrogenation
This diphosphonite ligand is effectively employed in Noyori-type asymmetric transfer hydrogenation of prochiral ketones. It enables the stereoselective reduction of carbonyl groups, yielding enantiomerically enriched alcohols.
Chiral Ligand in Catalysis
As a chiral catalyst ligand, it plays a crucial role in facilitating enantioselective transformations. Its application is key in the synthesis of chiral building blocks for complex organic molecules and pharmaceuticals.
Organic Synthesis Reagent
The compound serves as a vital reagent in advanced organic synthesis, particularly where precise control over stereochemistry is paramount. It contributes to the development of novel synthetic methodologies.
| Molecular weight | 838.82 |
|---|---|
| Empirical formula | C55H36O5P2 |
| Optical activity | [α]22/D +270°, c = 1 in chloroform |
| Application | This diphosphonite ligand has been successfully employed in Noyori-type asymmetric transfer hydrogenation of prochiral ketones.1 |
| Melting point | 198-217 °C |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (11bR,11′bR)-4,4′-(9,9-Dimethyl-9H-xanthene-4,5-diyl)bis-dinaphtho[2,1-d:1′, 2′-f][1,3,2]dioxaphosphepin used for?
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This compound is used as a chiral diphosphonite ligand in asymmetric synthesis, notably for Noyori-type asymmetric transfer hydrogenation of prochiral ketones.
What is the CAS number and formula for this chemical?
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The CAS number is 349114-63-2, and the empirical formula is C55H36O5P2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound as a research-grade chemical. We do not represent it as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated otherwise.
What are the safety and handling considerations for this product?
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This compound has a GHS classification indicating hazards. Refer to the Safety Data Sheet (SDS) for detailed information on handling, storage, and necessary personal protective equipment (PPE). Store in a cool, dry place.
How is this product packed, shipped, and exported?
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Tech Serve Solutions packs and ships this chemical in accordance with international regulations for hazardous materials. We are experienced global exporters of fine chemicals.
How can I request a sample or a quote?
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Please contact our sales team via the website or directly by email to request a sample or obtain a quotation for this product.
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