N,N,N′,N′-Tetramethylethylenediamine
N,N,N′,N′-Tetramethylethylenediamine (CAS: 110-18-9) is a tertiary diamine with the linear formula (CH₃)₂NCH₂CH₂N(CH₃)₂ and a molecular weight of 116.20 g/mol. This colourless liquid is primarily recognised for its potent catalytic activity in polymerisation reactions, particularly in the production of polyurethanes and epoxies. It also serves as a key reagent in organic synthesis, facilitating various chemical transformations.
- IUPAC
- 1,2-Bis(dimethylamino)ethane,TEMED,TMEDA
- Synonyms
- N,N′-Tetramethylethylenediamine110-18-9(CH3)2NCH2CH2N(CH3)21,2-Bis(dimethylamino)ethaneTEMEDTMEDA

Polymerisation Catalyst
N,N,N′,N′-Tetramethylethylenediamine acts as a highly effective catalyst in the polymerisation of polyurethanes and epoxy resins. Its tertiary amine structure promotes rapid curing and cross-linking, essential for material production.
Organic Synthesis Reagent
This compound is a versatile reagent in organic chemistry. It is employed as a base and nucleophile in a variety of synthetic pathways, including the preparation of complex organic molecules and intermediates.
Laboratory Accelerator
In biochemical laboratories, N,N,N′,N′-Tetramethylethylenediamine is frequently used as an accelerator for the polymerisation of acrylamide gels used in electrophoresis, such as SDS-PAGE.
| Molecular weight | 116.20 |
|---|---|
| Linear formula | (CH3)2NCH2CH2N(CH3)2 |
| Assay | ≥99.5% |
| Boiling point | 120-122 °C(lit.) |
| Density | 0.775 g/mL at 20 °C(lit.) |
| Refractive index | n20/D 1.4179(lit.) |
| Melting point | −55 °C(lit.) |



Hazard statements
- H225Highly flammable liquid and vapour
- H302Harmful if swallowed
- H314Causes severe skin burns and eye damage
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Flash point | 20 °C / 68 °F |
|---|---|
| Transport (UN / ADR) | UN 2372 3 / PGII |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | F,C |
| Risk statements (R) | 11-20/22-34 |
| Safety statements (S) | 16-26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Purified By | redistillation |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N,N,N′,N′-Tetramethylethylenediamine used for?
+
N,N,N′,N′-Tetramethylethylenediamine is primarily used as a catalyst in the polymerisation of polyurethanes and epoxy resins, and as an accelerator in acrylamide gel preparation for electrophoresis. It also functions as a reagent in organic synthesis.
What is the CAS number and chemical formula for N,N,N′,N′-Tetramethylethylenediamine?
+
The CAS number is 110-18-9 and the linear formula is (CH₃)₂NCH₂CH₂N(CH₃)₂.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies N,N,N′,N′-Tetramethylethylenediamine with an assay of ≥99.5%. We do not represent this product as USP, BP, or EP grade unless explicitly stated otherwise.
How should N,N,N′,N′-Tetramethylethylenediamine be handled safely?
+
N,N,N′,N′-Tetramethylethylenediamine is a flammable liquid and vapour, is harmful if swallowed or inhaled, and causes severe skin burns and eye damage (Danger: H225-H302 + H332-H314). Handle with appropriate personal protective equipment in a well-ventilated area, away from ignition sources.
Is N,N,N′,N′-Tetramethylethylenediamine a controlled substance?
+
Based on the provided data, N,N,N′,N′-Tetramethylethylenediamine is not indicated as a controlled substance. Please consult local regulations for specific requirements.
How is N,N,N′,N′-Tetramethylethylenediamine packed and shipped?
+
N,N,N′,N′-Tetramethylethylenediamine (UN 2372) is classified under UN packing group II for transport. TSS exports this chemical adhering to all relevant international shipping and handling regulations.
How can I request a quote or sample?
+
To request a quote or a sample of N,N,N′,N′-Tetramethylethylenediamine, please contact our sales team via the website or designated contact channels, specifying your requirements.
▶ Related products

3,4,5-Trimethoxybenzylamine
Organic Building Blocks

3,4-dihydroxyphenylacetone
Organic Building Blocks

3-Fluoro-4-methoxybenzonitrile
C8H6FNO
Organic Building Blocks
4-Ethyltoluene
C2H5C6H4CH3
Organic Building Blocks
Fluoroacetic acid
C2H3FO2
Organic Building Blocks
Methoxyacetaldehyde
C3H6O2
Organic Building Blocks
Methyl 4-acetamido-5-chloro-2-methoxybenzoate
Organic Building Blocks

Methyl 5-bromo-2-iodobenzoate
BrC6H3(I)CO2CH3
Organic Building Blocks▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis