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N,N,N′,N′-Tetramethylethylenediamine

CAS 110-18-9N′Organic Building Blocks

N,N,N′,N′-Tetramethylethylenediamine (CAS: 110-18-9) is a tertiary diamine with the linear formula (CH₃)₂NCH₂CH₂N(CH₃)₂ and a molecular weight of 116.20 g/mol. This colourless liquid is primarily recognised for its potent catalytic activity in polymerisation reactions, particularly in the production of polyurethanes and epoxies. It also serves as a key reagent in organic synthesis, facilitating various chemical transformations.

IUPAC
1,2-Bis(dimethylamino)ethane,TEMED,TMEDA
Synonyms
N,N′-Tetramethylethylenediamine110-18-9(CH3)2NCH2CH2N(CH3)21,2-Bis(dimethylamino)ethaneTEMEDTMEDA
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N,N,N′,N′-Tetramethylethylenediamine (N′) — chemical structure, CAS 110-18-9; Chemistry, fine chemical supplied by Tech Serve Solutions
Building BlocksChemical SynthesisNitrogen CompoundsOrganic Building BlocksPolyamines
01 /Applications

Polymerisation Catalyst

N,N,N′,N′-Tetramethylethylenediamine acts as a highly effective catalyst in the polymerisation of polyurethanes and epoxy resins. Its tertiary amine structure promotes rapid curing and cross-linking, essential for material production.

Organic Synthesis Reagent

This compound is a versatile reagent in organic chemistry. It is employed as a base and nucleophile in a variety of synthetic pathways, including the preparation of complex organic molecules and intermediates.

Laboratory Accelerator

In biochemical laboratories, N,N,N′,N′-Tetramethylethylenediamine is frequently used as an accelerator for the polymerisation of acrylamide gels used in electrophoresis, such as SDS-PAGE.

02 /Properties
Molecular weight116.20
Linear formula(CH3)2NCH2CH2N(CH3)2
Assay≥99.5%
Boiling point120-122 °C(lit.)
Density0.775 g/mL at 20 °C(lit.)
Refractive indexn20/D 1.4179(lit.)
Melting point−55 °C(lit.)
03 /Safety & handling
GHS hazard pictogram: Flammable (GHS02)
Flammable
GHS hazard pictogram: Corrosive (GHS05)
Corrosive
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Danger

Hazard statements

  • H225Highly flammable liquid and vapour
  • H302Harmful if swallowed
  • H314Causes severe skin burns and eye damage

Precautionary statements

  • P210Keep away from heat, sparks and open flames. No smoking
  • P280Wear protective gloves, clothing and eye/face protection
  • P305IF IN EYES
  • P310Immediately call a POISON CENTER or doctor
Flash point20 °C / 68 °F
Transport (UN / ADR)UN 2372 3 / PGII
Water hazard class (WGK, DE)1
Hazard codes (EU)F,C
Risk statements (R)11-20/22-34
Safety statements (S)16-26-36/37/39-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
110-18-9
Beilstein registry
1732991
05 /Additional specifications
Purified Byredistillation
06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is N,N,N′,N′-Tetramethylethylenediamine used for?

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N,N,N′,N′-Tetramethylethylenediamine is primarily used as a catalyst in the polymerisation of polyurethanes and epoxy resins, and as an accelerator in acrylamide gel preparation for electrophoresis. It also functions as a reagent in organic synthesis.

What is the CAS number and chemical formula for N,N,N′,N′-Tetramethylethylenediamine?

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The CAS number is 110-18-9 and the linear formula is (CH₃)₂NCH₂CH₂N(CH₃)₂.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies N,N,N′,N′-Tetramethylethylenediamine with an assay of ≥99.5%. We do not represent this product as USP, BP, or EP grade unless explicitly stated otherwise.

How should N,N,N′,N′-Tetramethylethylenediamine be handled safely?

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N,N,N′,N′-Tetramethylethylenediamine is a flammable liquid and vapour, is harmful if swallowed or inhaled, and causes severe skin burns and eye damage (Danger: H225-H302 + H332-H314). Handle with appropriate personal protective equipment in a well-ventilated area, away from ignition sources.

Is N,N,N′,N′-Tetramethylethylenediamine a controlled substance?

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Based on the provided data, N,N,N′,N′-Tetramethylethylenediamine is not indicated as a controlled substance. Please consult local regulations for specific requirements.

How is N,N,N′,N′-Tetramethylethylenediamine packed and shipped?

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N,N,N′,N′-Tetramethylethylenediamine (UN 2372) is classified under UN packing group II for transport. TSS exports this chemical adhering to all relevant international shipping and handling regulations.

How can I request a quote or sample?

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To request a quote or a sample of N,N,N′,N′-Tetramethylethylenediamine, please contact our sales team via the website or designated contact channels, specifying your requirements.

Need N,N,N′,N′-Tetramethylethylenediamine in a specific grade or volume?