N,O-Bis(trimethylsilyl)hydroxylamine
N,O-Bis(trimethylsilyl)hydroxylamine (CAS 22737-37-7) is a reactive organosilicon compound with the linear formula (CH3)3SiONHSi(CH3)3 and a molecular weight of 177.39 g/mol. It serves as a valuable building block in chemical synthesis, particularly for introducing silylated hydroxylamine functionalities. This compound is essential in organic chemistry research and development for creating complex molecules and intermediates, offering versatile reactivity in various synthetic pathways.
- Synonyms
- (CH3)3SiONHSi(CH3)3
Organic Synthesis Intermediate
Utilised as a key intermediate in the synthesis of complex organic molecules and pharmaceutical building blocks. Its silylated hydroxylamine structure allows for controlled introduction of nitrogen and oxygen functionalities.
Reagent for Silylation
Functions as a silylating agent in organic reactions. It can be used to protect hydroxyl or amino groups, or to facilitate transformations requiring silylated intermediates.
Research and Development
A useful reagent in academic and industrial research settings for exploring novel synthetic routes and developing new chemical entities. Its reactivity profile makes it suitable for diverse chemical transformations.
| Molecular weight | 177.39 |
|---|---|
| Linear formula | (CH3)3SiONHSi(CH3)3 |
| Assay | ≥97.0% (GC) |
| Boiling point | 78-80 °C/100 mmHg(lit.) |
| Density | 0.83 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.411(lit.) |
| Storage temperature | 2-8°C |
Hazard statements
- H226Flammable liquid and vapour
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 29 °C / 84.2 °F |
| Transport (UN / ADR) | UN 2920 3(8) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 10-34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N,O-Bis(trimethylsilyl)hydroxylamine used for?
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N,O-Bis(trimethylsilyl)hydroxylamine is primarily used as a building block and intermediate in organic synthesis and silylation reactions within research and development settings.
What are the CAS number and formula for N,O-Bis(trimethylsilyl)hydroxylamine?
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The CAS number is 22737-37-7 and the linear formula is (CH3)3SiONHSi(CH3)3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies N,O-Bis(trimethylsilyl)hydroxylamine with an assay of ≥97.0% (GC). We do not represent this product as USP, BP, EP or other pharmacopoeia grades.
What are the safety considerations when handling N,O-Bis(trimethylsilyl)hydroxylamine?
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N,O-Bis(trimethylsilyl)hydroxylamine is a flammable liquid and vapour (H226) and causes severe skin burns and eye damage (H314). Appropriate personal protective equipment, including gloves, eye protection, and respiratory protection, must be used. Handle in a well-ventilated area, away from ignition sources.
How is N,O-Bis(trimethylsilyl)hydroxylamine packaged and shipped?
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N,O-Bis(trimethylsilyl)hydroxylamine is shipped according to UN 2920 3(8) / PGII regulations. Please contact us for specific packaging and export details.
How can I request a sample or quote for N,O-Bis(trimethylsilyl)hydroxylamine?
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To request a sample or quote, please contact our sales team through the website or by phone, providing the product name and CAS number (22737-37-7).
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