N,N′-Terephthalylidene-bis(4-methoxyaniline)
N,N′-Terephthalylidene-bis(4-methoxyaniline) (CAS: 3525-51-7) is an organic compound with the molecular formula C22H20N2O2 and a molecular weight of 344.41 g/mol. This Schiff base serves as a valuable building block in organic synthesis. It finds application in the creation of more complex molecules and as a component in material science research, offering a unique structural motif for chemical exploration.
- IUPAC
- N,N′-(1,4-Phenylenedimethylidene)bis(4-methoxyaniline),N,N′-Terephthalylidenedi-p-anisidine,Terephthalbis(4-methoxyaniline),Terephthalbis(p-anisidine)
- Synonyms
- C22H20N2O2N,N′-(1,4-Phenylenedimethylidene)bis(4-methoxyaniline)N,N′-Terephthalylidenedi-p-anisidineTerephthalbis(4-methoxyaniline)Terephthalbis(p-anisidine)

Organic Synthesis Intermediate
Utilised as a key intermediate in the synthesis of diverse organic compounds, particularly those involving imine or Schiff base functionalities. Its structure makes it suitable for further chemical modifications.
Material Science Research
Explored for its potential in developing novel organic materials, including polymers and functional dyes, owing to its conjugated system and nitrogen-containing structure.
Ligand Development
Can serve as a precursor or component in the design of ligands for coordination chemistry, potentially forming complexes with various metal ions.
| Molecular weight | 344.41 |
|---|---|
| Empirical formula | C22H20N2O2 |
| Assay | 97% |
| Melting point | 223-227 °C(lit.) |


Hazard statements
- H315Causes skin irritation
- H317May cause an allergic skin reaction
- H319Causes serious eye irritation
- H334May cause allergy or asthma symptoms if inhaled
- H335May cause respiratory irritation
- H413May cause long-lasting harmful effects to aquatic life
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P342
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 36/37/38-42/43 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N,N′-Terephthalylidene-bis(4-methoxyaniline) used for?
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N,N′-Terephthalylidene-bis(4-methoxyaniline) is primarily used as a building block in organic synthesis and in material science research. It can act as an intermediate for creating more complex organic molecules and is explored for developing new organic materials.
What are the CAS number and formula for N,N′-Terephthalylidene-bis(4-methoxyaniline)?
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The CAS number for N,N′-Terephthalylidene-bis(4-methoxyaniline) is 3525-51-7, and its empirical formula (Hill notation) is C22H20N2O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies N,N′-Terephthalylidene-bis(4-methoxyaniline) with an assay of 97%. We do not represent this product as USP, BP, EP, or pharmaceutical grade.
How should N,N′-Terephthalylidene-bis(4-methoxyaniline) be handled?
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N,N′-Terephthalylidene-bis(4-methoxyaniline) is classified under GHS07 and GHS08 with a Danger signal word. It can cause skin irritation (H315), allergic skin reactions (H317), serious eye irritation (H319), and may cause allergy or asthma symptoms or breathing difficulties if inhaled (H334), and may irritate the respiratory tract (H335). It may also cause long lasting harmful effects to aquatic life (H413). Recommended personal protective equipment includes a dust mask type N95 (US), eyeshields, faceshields, and gloves. Handle with adequate ventilation, avoiding dust formation. Refer to the Safety Data Sheet for comprehensive handling instructions.
Is N,N′-Terephthalylidene-bis(4-methoxyaniline) a controlled substance?
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The provided data does not indicate that N,N′-Terephthalylidene-bis(4-methoxyaniline) is a controlled substance.
How is this chemical packed and shipped?
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Tech Serve Solutions ensures chemicals are packed and exported according to international shipping and safety regulations. Specific packaging details will be provided upon request and order confirmation.
How can I request a sample or quote for N,N′-Terephthalylidene-bis(4-methoxyaniline)?
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To request a sample or a quote, please contact our sales department through the website or by phone. Please include the product name and CAS number (3525-51-7) in your inquiry.
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