N-Bromophthalimide
N-Bromophthalimide (CAS: 2439-85-2) is an organic compound with the molecular formula C8H4BrNO2 and a molecular weight of 226.03 g/mol. This light yellow crystalline solid serves as a versatile brominating reagent and building block in organic synthesis. Its applications include allylic amination, asymmetric bromination of biaryl derivatives, and use in titrimetric analysis. Supplied by Tech Serve Solutions, it is available in a minimum 95% purity.
Reagent in Allylic Amination
N-Bromophthalimide is employed as a reagent in the allylic amination of alkenes, facilitating the introduction of amine functionalities at allylic positions.
Asymmetric Bromination
It functions as a brominating agent in enantioselective synthesis, specifically in the chiral phosphoric acid-catalyzed asymmetric bromination of multisubstituted biaryl derivatives.
Titrimetric Determination
N-Bromophthalimide can be utilised as a titrant for the quantitative determination of isoniazid, both in its pure form and within pharmaceutical tablet formulations.
| Molecular weight | 226.03 |
|---|---|
| Empirical formula | C8H4BrNO2 |
| Assay | 95% |
| Application | N-Bromophthalimide has been used:• as reagent in allylic amination reactions of alkenes1• brominating reagent in enantioselective synthesis of multisubstituted biaryl derivatives by chiral phosphoric acid catalyzed asymmetric bromination2• as a titrant in titrimetric determination of isoniazid in pure form or in tablets3 |
| Melting point | 194-198 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-Bromophthalimide used for?
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N-Bromophthalimide is primarily used as a brominating reagent in organic synthesis, including applications in allylic amination and asymmetric bromination. It also finds use in the titrimetric determination of isoniazid.
What is the CAS number and formula for N-Bromophthalimide?
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The CAS number for N-Bromophthalimide is 2439-85-2, and its empirical formula is C8H4BrNO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies N-Bromophthalimide with a minimum assay of 95%. We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
What are the safety considerations for handling N-Bromophthalimide?
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N-Bromophthalimide is classified with GHS07 symbol and a Warning signal word. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (type N95), eyeshields, and gloves, should be used. Handle in a well-ventilated area.
Is N-Bromophthalimide a controlled substance?
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The provided data does not indicate that N-Bromophthalimide is a controlled substance.
How is N-Bromophthalimide packed and shipped?
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N-Bromophthalimide is carefully packed and exported globally by Tech Serve Solutions in compliance with all relevant shipping regulations for chemical compounds.
How can I request a quote or sample for N-Bromophthalimide?
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To request a quote or a sample of N-Bromophthalimide, please contact our sales team through the website or via direct inquiry.
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