N-Boc-ethylenediamine
N-Boc-ethylenediamine (CAS: 57260-73-8) is a protected diamine with the linear formula (CH3)3COCONHCH2CH2NH2 and a molecular weight of 160.21 g/mol. This organic building block, featuring a tert-butoxycarbonyl (Boc) protected amine, is a versatile intermediate in chemical synthesis. It is primarily utilised in the construction of more complex molecules, serving as a linker or a precursor in the development of pharmaceutical compounds and biochemical probes.
- IUPAC
- N-Boc-1,2-diaminoethane,tert-Butyl N-(2-aminoethyl)carbamate
- Synonyms
- tert-Butyl N-(2-aminoethyl)carbamateN-(2-Aminoethyl)-N-tert-butoxycarbonylN-Boc-1,2-diaminoethane
Pharmaceutical Intermediate
N-Boc-ethylenediamine serves as a crucial building block in the synthesis of active pharmaceutical ingredients (APIs). Its protected amine functionality allows for selective reactions, enabling the controlled construction of complex drug molecules.
Chemical Synthesis Reagent
As an organic building block, this compound is employed in general chemical synthesis. The Boc protecting group can be readily removed under acidic conditions, revealing a primary amine for further functionalization.
Bioconjugation and Linker Chemistry
The structure of N-Boc-ethylenediamine makes it suitable for use in developing linkers and crosslinkers. It can be incorporated into molecules designed for bioconjugation or for creating spacered functionalities in chemical biology applications.
| Molecular weight | 160.21 |
|---|---|
| Linear formula | (CH3)3COCONHCH2CH2NH2 |
| Assay | ≥98.0% (NT) |
| Boiling point | 72-80 °C/0.1 mmHg(lit.) |
| Density | 1.012 g/mL at 20 °C(lit.) |
| Refractive index | n20/D 1.458(lit.)n20/D 1.458 |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Transport (UN / ADR) | UN 2735PSN1 8 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-Boc-ethylenediamine primarily used for?
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N-Boc-ethylenediamine is primarily used as a protected building block in organic synthesis, particularly in the pharmaceutical industry and for creating linkers in chemical biology. The Boc group allows for selective manipulation of the molecule's amine functionalities.
What are the CAS number and linear formula for N-Boc-ethylenediamine?
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The CAS number for N-Boc-ethylenediamine is 57260-73-8, and its linear formula is (CH3)3COCONHCH2CH2NH2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies N-Boc-ethylenediamine with an assay of ≥98.0% (NT). We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated in the product specifications.
How should N-Boc-ethylenediamine be handled safely?
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N-Boc-ethylenediamine is classified as Danger (GHS05) and causes severe skin burns and eye damage (H314). Appropriate personal protective equipment, including full-face shields, chemical-resistant gloves, and eye protection, must be worn. Handle in a well-ventilated area and have emergency procedures in place.
How is N-Boc-ethylenediamine packed and exported by TSS?
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Tech Serve Solutions reliably packs and exports fine chemicals globally, adhering to all necessary regulations for safe transportation. Specific packaging details can be provided upon request.
How can I request a sample or quote for N-Boc-ethylenediamine?
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To request a sample or a quotation for N-Boc-ethylenediamine, please contact our sales team through the website or by phone, providing your specific requirements.
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