N-Boc-p-phenylenediamine
N-Boc-p-phenylenediamine (CAS: 71026-66-9) is a protected amine derivative with the linear formula (CH₃)₃COCONHC₆H₄NH₂ and a molecular weight of 208.26 g/mol. This compound serves as a valuable building block in organic synthesis, particularly for introducing protected amine functionalities into more complex molecules. Its protected nature allows for selective reactions, making it a key intermediate in the development of various chemical entities.
- IUPAC
- 4-(tert-Butoxycarbonylamino)aniline,tert-Butyl-4-aminophenylcarbamate
- Synonyms
- tert-Butyl (4-aminophenyl)carbamate4-(tert-Butoxycarbonylamino)anilinetert-Butyl N-(4-aminophenyl)carbamate4-aminophenylcarbamic acid tert-butyl ester
Organic Synthesis Intermediate
N-Boc-p-phenylenediamine acts as a versatile intermediate in multi-step organic syntheses. The tert-butoxycarbonyl (Boc) protecting group enables selective functionalization of the aromatic ring or the unprotected amine, facilitating controlled chemical transformations.
Building Block for Complex Molecules
This compound is utilised as a fundamental building block in the construction of more elaborate molecular architectures. Its bifunctional nature, with a protected amine and a free amine, allows for diverse coupling reactions.
Chemical Biology Research
In chemical biology, N-Boc-p-phenylenediamine can be incorporated into probes or labelling reagents. The ability to deprotect the amine selectively under specific conditions makes it useful for controlled conjugation strategies.
Linker and Crosslinker Development
The molecule's structure lends itself to the development of linkers and crosslinkers used in bioconjugation or material science. Modifications can be made to either amine group after selective protection/deprotection steps.
| Molecular weight | 208.26 |
|---|---|
| Linear formula | (CH3)3COCONHC6H4NH2 |
| Assay | ≥97.0% (NT) |
Hazard statements
- H302Harmful if swallowed
- H317May cause an allergic skin reaction
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 3077 9 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn,N |
| Risk statements (R) | 22-43-50/53 |
| Safety statements (S) | 36/37-60-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-Boc-p-phenylenediamine used for?
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N-Boc-p-phenylenediamine is primarily used as an intermediate and building block in organic synthesis, chemical biology research, and in the development of linkers and crosslinkers.
What are the CAS number and formula for N-Boc-p-phenylenediamine?
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The CAS number is 71026-66-9 and the linear formula is (CH₃)₃COCONHC₆H₄NH₂.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies N-Boc-p-phenylenediamine with an assay of ≥97.0%. This product is suitable for research and technical applications. TSS does not represent this product as USP, BP, EP, or other pharmacopoeial grades.
What are the key safety concerns when handling N-Boc-p-phenylenediamine?
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N-Boc-p-phenylenediamine is classified as harmful if swallowed (H302) and may cause an allergic skin reaction (H317). Appropriate personal protective equipment, including a dust mask (N95), eyeshields, face shields, and gloves, must be used. Avoid contact with skin and eyes, and ensure adequate ventilation.
Is N-Boc-p-phenylenediamine suitable for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, and N-Boc-p-phenylenediamine can be exported. Shipping is compliant with relevant dangerous goods regulations (UN 3077, Class 9, Packing Group III).
How can I request a sample or quote for N-Boc-p-phenylenediamine?
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To request a sample or a quote, please contact the Tech Serve Solutions sales team through the website or by phone, providing the product name and CAS number (71026-66-9).
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