N-Boc-hydroxylamine

CAS 36016-38-3(CH3)3COCONHOHOrganic Building Blocks

N-Boc-hydroxylamine (CAS 36016-38-3) is a derivative of hydroxylamine protected with a tert-butoxycarbonyl (Boc) group. This organic compound, with a molecular weight of 133.15 g/mol, serves as a valuable building block in organic synthesis. Its primary utility lies in its ability to introduce the hydroxylamine moiety into molecules under controlled conditions, making it useful in pharmaceutical research and the development of new chemical entities.

IUPAC: tert-Butyl N-hydroxycarbamate
Synonyms: tert-Butyl N-hydroxycarbamate

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N-Boc-hydroxylamine ((CH3)3COCONHOH) — chemical structure, CAS 36016-38-3; Chemistry, fine chemical supplied by Tech Serve Solutions

Building BlocksChemical SynthesisNitrogen CompoundsOrganic Building BlocksProtected Amines

01 /Applications

Organic Synthesis Reagent

N-Boc-hydroxylamine functions as a protected form of hydroxylamine, enabling selective reactions in complex synthetic pathways. The Boc group can be readily removed under acidic conditions, liberating the reactive hydroxylamine functionality.

Pharmaceutical Intermediate

It is employed as a key intermediate in the synthesis of various pharmaceutically active compounds. The controlled introduction of nitrogen-oxygen bonds is critical in the construction of drug molecules.

Building Block for Heterocycles

This compound can be utilised in the formation of nitrogen-containing heterocyclic rings, which are prevalent structures in many bioactive molecules and advanced materials.

02 /Properties

Molecular weight	133.15
Linear formula	(CH3)3COCONHOH
Assay	≥98.0% (N)
Storage temperature	2-8°C
Melting point	53-55 °C(lit.)53-55 °C

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

36016-38-3

MDL number

MFCD00002107

PubChem substance

24853547

Beilstein registry

1756546

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is N-Boc-hydroxylamine used for?

N-Boc-hydroxylamine is used as a protected hydroxylamine reagent in organic synthesis, particularly as an intermediate in the development of pharmaceuticals and other complex organic molecules.

What is the CAS number and formula for N-Boc-hydroxylamine?

The CAS number is 36016-38-3, and its linear formula is (CH3)3COCONHOH.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies N-Boc-hydroxylamine with an assay of ≥98.0% (N). This product is suitable for research and chemical synthesis purposes. Tech Serve Solutions does not represent this product as USP, BP, or EP grade.

How should N-Boc-hydroxylamine be handled and stored?

N-Boc-hydroxylamine should be handled with appropriate personal protective equipment, including eyeshields and gloves. A type N95 respirator filter is recommended. It should be stored at a temperature of 2-8°C.